Results 1 to 10 of about 663,608 (111)
Background: Cognitive deficits are common in multiple sclerosis (MS) and affect patients at all stages of the disease, regardless of phenotype. Aims: This literature review focuses the cognitive deficits observed in secondary progressive MS (SPMS). It is
Bruno Brochet +8 more
doaj +3 more sources
Extracellular Vesicle-Associated miRNA in Multiple Sclerosis Subtypes: Differential Profiles in Secondary Progressive Disease and the Effect of One-Year Siponimod Treatment [PDF]
Circulating extracellular vesicle-associated microRNAs (EV-miRNAs) are emerging as promising peripheral biomarkers in multiple sclerosis (MS). This prospective, observational pilot study was conceived as a hypothesis-generating investigation to ...
Oana Vrînceanu +4 more
doaj +2 more sources
Economic burden of secondary progressive multiple sclerosis: DISCOVER study [PDF]
Background To estimate the socioeconomic burden of people with secondary progressive multiple sclerosis (pwSPMS), considering direct health care, direct non-health care, and indirect costs, and to evaluate the relationship between costs and patients ...
Celia Oreja-Guevara +37 more
doaj +2 more sources
Rituximab in secondary progressive multiple sclerosis: a meta‐analysis [PDF]
Objective To evaluate the efficacy of rituximab (RTX) in stabilizing disability progression in secondary progressive multiple sclerosis (SPMS). Methods A systematic review was conducted, encompassing studies from inception to April 2023, utilizing the ...
Pasin Intarakhao +7 more
doaj +2 more sources
Background: The long-term prognosis of relapsing-remitting multiple sclerosis (RRMS) is usually unfavorable as most patients transition to secondary progressive multiple sclerosis (SPMS) with accumulative disability.
Qi Wu +8 more
doaj +2 more sources
Radiotherapy Improves the Disability in Patients with Secondary Progressive Multiple Sclerosis [PDF]
Background: Multiple sclerosis (MS) as a complex neurological abnormality is marked with loss of myelin and axons due to chronic inflammatory and autoimmune responses.
Hossein-Ali Ebrahimi +3 more
doaj +2 more sources
Sajida Sabsabi,1 Elio Mikhael,2 Georges Jalkh,1 Gabrielle Macaron,1,3 Mary Rensel3 1Department of Neurology, Hotel Dieu de France Hospital, Saint Joseph University, Beirut, Lebanon; 2Department of Internal Medicine, Hotel Dieu de France Hospital, Saint ...
Sabsabi S +4 more
doaj +2 more sources
Brain reserve and physical disability in secondary progressive multiple sclerosis [PDF]
Background The brain reserve hypothesis posits that larger maximal lifetime brain growth (MLBG) may confer protection against physical disability in multiple sclerosis (MS).
+52 more
doaj +2 more sources
The risk of secondary progressive multiple sclerosis is geographically determined but modifiable [PDF]
Richard Macdonell +2 more
exaly +2 more sources
Advances in clinical diagnosis of secondary progressive multiple sclerosis [PDF]
Multiple sclerosis(MS) is a chronic inflammatory disease of the central nervous system that involves demyelination and axonal degeneration. Usually, MS begins with a relapsing-remitting MS (RRMS) course, and approxi mately will develop into secondary ...
ZHANG Chao, GAO Xue
doaj +1 more source

