Results 31 to 40 of about 19,445,077 (386)

Secondary structure of the SARS-CoV-2 5’-UTR

RNA Biology, 2020
The SARS-CoV-2, a positive-sense single-stranded RNA Coronavirus, is a global threat to human health. Thus, understanding its life cycle mechanistically would be important to facilitate the design of antiviral drugs.
Zhichao Miao, Antonin Tidu, G. Eriani, F. Martin   +3 more
semanticscholar   +1 more source

Multi-objective genetic algorithm for pseudoknotted RNA sequence design

Frontiers in Genetics, 2012
RNA inverse folding is a computational technology for designing RNA sequences which fold into a user-specified secondary structure. Although pseudoknots are functionally important motifs in RNA structures, less reports concerning the inverse folding of ...
Akito eTaneda
doaj   +1 more source

Multiple structural alignment for distantly related all b structures using TOPS pattern discovery and simulated annealing [PDF]

, 2003
Topsalign is a method that will structurally align diverse protein structures, for example, structural alignment of protein superfolds. All proteins within a superfold share the same fold but often have very low sequence identity and different biological
Gilbert, D, Westhead, DR, Williams, A
core   +1 more source

Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy

Nucleic Acids Research, 2020
The current pandemic situation caused by the Betacoronavirus SARS-CoV-2 (SCoV2) highlights the need for coordinated research to combat COVID-19. A particularly important aspect is the development of medication.
A. Wacker, Julia E. Weigand, Sabine R. Akabayov, Nadide Altincekic, J. Bains, Elnaz Banijamali, O. Binas, Jesús Castillo-Martínez, E. Çetiner, B. Ceylan, Liang-Yuan Chiu, Jesse Davila-Calderon, K. Dhamotharan, E. Duchardt-Ferner, J. Ferner, L. Frydman, B. Fürtig, J. Gallego, J. T. Grün, C. Hacker, Christina Haddad, Martin Hähnke, M. Hengesbach, Fabian Hiller, Katharina F. Hohmann, Daniel Hymon, Vanessa de Jesus, H. Jonker, Heiko Keller, Božana Knezic, Tom Landgraf, F. Löhr, Le Luo, K. Mertinkus, C. Muhs, Mihajlo Novakovic, Andreas Oxenfarth, Martina Palomino-Schätzlein, Katja Petzold, S. A. Peter, D. Pyper, N. Qureshi, Magdalena Riad, C. Richter, K. Saxena, Tatjana Schamber, T. Scherf, Judith Schlagnitweit, A. Schlundt, Robbin Schnieders, Harald Schwalbe, Alvaro Simba-Lahuasi, S. Sreeramulu, E. Stirnal, Alexey Sudakov, Jan-Niklas Tants, B. Tolbert, Jennifer Vögele, Lena Weiß, Julia Wirmer‐Bartoschek, Maria A Wirtz Martin, J. Wöhnert, Heidi Zetzsche   +62 more
semanticscholar   +1 more source

SumSec: Accurate Prediction of Sumoylation Sites Using Predicted Secondary Structure

Molecules, 2018
Post Translational Modification (PTM) is defined as the modification of amino acids along the protein sequences after the translation process. These modifications significantly impact on the functioning of proteins.
Abdollah Dehzangi, Yosvany López, Ghazaleh Taherzadeh, Alok Sharma, Tatsuhiko Tsunoda   +4 more
doaj   +1 more source

Analyzing Secondary Structure Patterns in DNA Aptamers Identified via CompELS

Molecules, 2019
In contrast to sophisticated high-throughput sequencing tools for genomic DNA, analytical tools for comparing secondary structure features between multiple single-stranded DNA sequences are less developed.
Richard Sullivan, Mary Catherine Adams, Rajesh R. Naik, Valeria T. Milam   +3 more
doaj   +1 more source

RNA secondary structure prediction using an ensemble of two-dimensional deep neural networks and transfer learning

Nature Communications, 2019
The majority of our human genome transcribes into noncoding RNAs with unknown structures and functions. Obtaining functional clues for noncoding RNAs requires accurate base-pairing or secondary-structure prediction.
Jaswinder Singh, Jack Hanson, K. Paliwal, Yaoqi Zhou   +3 more
semanticscholar   +1 more source

Effects of heat treatment at two temperatures on the myosin cluster of bighead carp for gel formation

CyTA - Journal of Food, 2017
The α-helix of myosin decreased and the diameter of the myosin clusters increased monotonically with increasing heating time at 50 and 90°C. The clusters that formed during heating at 90°C were much larger than those that formed at 50°C.
Li Yuan, Yan-ai Liu, Jing Ge, Xue-ping Feng, Rui-chang Gao   +4 more
doaj   +1 more source

Recombinant Goose Circoviruses Circulating in Domesticated and Wild Geese in Poland

Viruses, 2018
Circoviruses are circular single-stranded DNA (ssDNA) viruses that infect a variety of animals, both domestic and wild. Circovirus infection in birds is associated with immunosuppression and this in turn predisposes the infected animals to secondary ...
Tomasz Stenzel, Daria Dziewulska, Brejnev M. Muhire, Penelope Hartnady, Simona Kraberger, Darren P. Martin, Arvind Varsani   +6 more
doaj   +1 more source

Single point mutations at the S129 residue of α-synuclein and their effect on structure, aggregation, and neurotoxicity

Frontiers in Chemistry, 2023
Parkinson’s disease is an age-related neurological disorder, and the pathology of the disease is linked to different types of aggregates of α-synuclein or alpha-synuclein (aS), which is an intrinsically disordered protein. The C-terminal domain (residues
Esha Pandit, Lopamudra Das, Anoy Kumar Das, Sandip Dolui, Saumen Saha, Uttam Pal, Animesh Mondal, Joydeep Chowdhury, Subhas C. Biswas, Nakul C. Maiti   +9 more
doaj   +1 more source