Results 101 to 110 of about 11,591,695 (294)

Design, Synthesis, and Biological Evaluation of New Analogs of Aurein 1.2 Containing Non-Proteinogenic Amino Acids

open access: yesMolecules
Extensive use of classical antibiotics has led to the growing emergence of many resistant strains of pathogenic bacteria. To combat this challenge, researchers have turned to the antimicrobial peptides (AMPs).
Nora Angelova   +6 more
doaj   +1 more source

Secondary structure prediction of vaccine construct.

open access: yes
Secondary structure prediction of vaccine construct.
Asifullah Khan (5901902)   +8 more
core   +1 more source

Accurate prediction of genome-wide RNA secondary structure profile based on extreme gradient boosting

open access: yes, 2020
For permissions, please e-mail: journals.permissions@oup.com Motivation: RNA secondary structure plays a vital role in fundamental cellular processes, and identification of RNA secondary structure is a key step to understand RNA functions.
Xiao, N   +11 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

The influence of tertiary structure on secondary structure prediction

open access: yesFEBS Letters, 1985
The secondary structure prediction algorithm of Garnier et al. [(1978) J. Mol. Biol. 120, 97‐120] has been used for 16 proteins whose structures are dominated by β‐sheet. Comparisons of the predicted structures with those defined by the algorithm of Kabch and Sander [(1983) Biopolymers 22, 2577‐2637] shows that for β‐sheet residues, the quality of ...
Garratt, Richard C.   +2 more
openaire   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Methods for prediction of RNA secondary structure

open access: yes, 2021
This bachelor thesis discuss RNA secondary structure and it’s prediction in particular. It describes various secondary structure elements and presents some secondary structure prediction methods.
Polzerová, Nikola
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

NN-PRED: A novel consensus secondary structure prediction program using neural networks

open access: yesRevista UIS Ingenierías, 2013
In this paper, a new program for protein secondary structure prediction is proposed. The program, which is called NN-Pred, allows multiple sequences to be submitted and it returns predictions from fve secondary structure prediction algorithms.
Oscar Fernando Bedoya Leiva   +1 more
doaj  

PROTEUS2: A Web Server for Comprehensive Protein Structure Prediction and Structure-Based Annotation [PDF]

open access: yes, 2008
PROTEUS2 is a web server designed to support comprehensive protein structure prediction and structure-based annotation. PROTEUS2 accepts either single sequences (for directed studies) or multiple sequences (for whole proteome annotation) and predicts the
Wishart, D.S.   +5 more
core   +1 more source

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