Results 81 to 90 of about 11,591,695 (294)

A New Method of RNA Secondary Structure Prediction Based on Convolutional Neural Network and Dynamic Programming

open access: yesFrontiers in Genetics, 2019
In recent years, obtaining RNA secondary structure information has played an important role in RNA and gene function research. Although some RNA secondary structures can be gained experimentally, in most cases, efficient, and accurate computational ...
Hao Zhang   +6 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

An evolutionary method for learning HMM structure: prediction of protein secondary structure

open access: yesBMC Bioinformatics, 2007
Background The prediction of the secondary structure of proteins is one of the most studied problems in bioinformatics. Despite their success in many problems of biological sequence analysis, Hidden Markov Models (HMMs) have not been used much for this ...
Won Kyoung-Jae   +3 more
doaj   +1 more source

Combining Deep Neural Networks for Protein Secondary Structure Prediction

open access: yesIEEE Access, 2020
By combining convolutional neural networks (CNN) and long short term memory networks (LSTM) into the learning structure, this paper presents a supervised learning method called combining deep neural networks (CDNN) for protein secondary structure ...
Shusen Zhou   +4 more
doaj   +1 more source

Study of RNA Secondary Structure Prediction Algorithms

open access: yes, 2011
RNA secondary structure study is one of the most important fields in computational molecular biology. According to different conditions, RNA secondary structure prediction derives two ways.
Ying Sun, Sheng Hua Ye, Hong Wei Lu
core   +1 more source

Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics [PDF]

open access: yes, 2004
Reeder J, Giegerich R. Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics. BMC Bioinformatics. 2004;5(1): 104.Background: The general problem of RNA secondary structure prediction under the widely ...
Reeder Jens   +5 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Potato virus A coat protein secondary structure prediction.

open access: yes, 2013
Potato virus A coat protein secondary structure prediction.
Lilian Järvekülg (294005)   +8 more
core   +1 more source

JPred:a consensus secondary structure prediction server [PDF]

open access: yes, 1998
UNLABELLED: An interactive protein secondary structure prediction Internet server is presented. The server allows a single sequence or multiple alignment to be submitted, and returns predictions from six secondary structure prediction algorithms that ...
Barton, G J; id_orcid   +9 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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