Results 161 to 170 of about 18,178,221 (305)

RNAStructuromeDB: a transcriptome-wide database of predicted RNA secondary structures with integrated APIs for functional annotation and RNA-targeted drug discovery. [PDF]

NAR Genom Bioinform
Dapour AO, Manigrasso J, Rouse WB, La Sala G, Aronnax MV, De Maria L, Hamilton RS, Cuesta SM, Hogner A, Moss WN.   +9 more
europepmc   +1 more source

Distinct circular dichroism spectroscopic signatures of polyproline II and unordered secondary structures: Applications in secondary structure analyses

Protein Science, 2014
J. L. Lopes, A. Miles, L. Whitmore, B. Wallace   +3 more
semanticscholar   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

TARNAS: A Software Tool for Abstracting and Translating RNA Secondary Structures. [PDF]

Int J Mol Sci
Quadrini M, Canchari PH, Rosati P, Tesei L.   +3 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Comparative study on starch and protein secondary structures in brown, red, and black rice influenced by microwave treatment. [PDF]

Food Chem X
Pintilii C, Baia M, Alexa E, Magyari K, Botiz I, Muresan-Pop M, Barbu-Tudoran L, Nicula C, Peter A, Szakács Z, Cozmuta AM, Cozmuta LM.   +11 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

ECSFinder: optimized prediction of evolutionarily conserved RNA secondary structures from genome sequences. [PDF]

Nucleic Acids Res
Gaonac'h-Lovejoy V, Mattick JS, Sauvageau M, Smith MA.   +3 more
europepmc   +1 more source

Mono-valent salt corrections for RNA secondary structures in the ViennaRNA package. [PDF]

Algorithms Mol Biol, 2023
Yao HT, Lorenz R, Hofacker IL, Stadler PF.   +3 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source