Results 91 to 100 of about 34,970 (301)

Plasma LEAP2 concentration is associated with energy intake and postprandial insulin increase depending on meal size but not weight status in men

Diabetes, Obesity and Metabolism, Volume 27, Issue 8, Page 4427-4435, August 2025.
Abstract Aims While LEAP2 is increasingly recognized as an appetite‐regulating hormone, its role in meal regulation and the dynamics of postprandial LEAP2 concentrations remain poorly understood in humans. The aim of the study was to (1) assess postprandial LEAP2 concentrations following a recommended‐energy breakfast, exploring potential association ...
María F. Andreoli, Pablo N. De Francesco, Olga E. Titova, Mario Perello, Helgi B. Schiöth   +4 more
wiley   +1 more source

Ghrelin and growth hormone secretagogues (GHS): modulation of growth hormone secretion and therapeutic applications [PDF]

, 2008
Growth hormone-releasing hormone (GHRH) and somatostatin modulate growth hormone (GH) secretion. A third mechanism was discovered in the last decade, involving the action of growth hormone secretagogues (GHS).
Correa-Silva, Silvia R., Lengyel, Ana Maria Judith, Sa, Larissa Bianca Paiva Cunha de   +2 more
core   +2 more sources

What is the ‘real‐world’ experience with fixed‐ratio combination therapy (insulin + GLP‐1 receptor agonist) in routine clinical practice? Take‐home messages for clinicians regarding key outcomes

Diabetes, Obesity and Metabolism, Volume 27, Issue S7, Page 26-41, August 2025.
Abstract Aims The fixed‐ratio combinations (FRCs) of a basal insulin and glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA), IDegLira (insulin degludec/liraglutide) and iGlarLixi (insulin glargine/lixisenatide), offer a once‐daily injectable treatment option for adults with type 2 diabetes (T2D), combining complementary mechanisms of action to target ...
Juan Pablo Frias
wiley   +1 more source

Effects of Different Plant Density and Cutting Times on Yield of Stevia under the Çukurova Conditions

International Journal of Secondary Metabolite, 2017
Stevia (Stevia rebaudiana Bertoni) is perennial shrub form plant belonging to Asteraceae. It is indigenous to Paraguay and Brazil. Stevia is a natural sweetening and it has using potential to diets of obesity patients with non-caloric specialty and ...
Leyla Sezer Tansı, Elnaz Samadpourrigani, Selin Gedik   +2 more
doaj   +1 more source

Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin [PDF]

, 2006
Growth hormone secretion is classically modulated by two hypothalamic hormones, growth hormone-releasing hormone and somatostatin. A third pathway was proposed in the last decade, which involves the growth hormone secretagogues.
Lengyel, Ana Maria Judith
core   +2 more sources

Identification and functional analysis of novel human growth hormone secretagogue receptor (GHSR) gene mutations in Japanese subjects with short stature.

Journal of Clinical Endocrinology and Metabolism, 2011
CONTEXT Short stature (SS) is a multifactorial developmental condition with a significant genetic component. Recent studies have revealed that rare deleterious mutations in the GH-secretagogue receptor type 1A (GHSR1A) gene could be a cause of familial ...
H. Inoue, Natsumi Kangawa, Atsuko Kinouchi, Y. Sakamoto, C. Kimura, R. Horikawa, Y. Shigematsu, M. Itakura, T. Ogata, K. Fujieda   +9 more
semanticscholar   +1 more source

Management of Constipation in Eating Disorders—A Scoping Review

Journal of Human Nutrition and Dietetics, Volume 38, Issue 4, August 2025.
ABSTRACT Background Constipation is a common nutrition impact symptom experienced by the eating disorder population. Objective The aim of this scoping review was to identify current recommendations and evidence for managing constipation within the eating disorders population, specifically anorexia nervosa (AN) and bulimia nervosa (BN).
Bridget Heathcote, Sharon Carey
wiley   +1 more source

Ghrelin receptors in non-mammalian vertebrates

Frontiers in Endocrinology, 2013
The growth hormone secretagogue-receptor (GHS-R) was discovered in humans and pigs in 1996. The endogenous ligand, ghrelin, was discovered three years later, in 1999, and our understanding of the physiological significance of the ghrelin system in ...
Hiroyuki eKaiya, Kenji eKangawa, Mikiya eMiyazato   +2 more
doaj   +1 more source

Ghrelin and lipid metabolism: key partners in energy balance [PDF]

, 2010
Disclaimer: this is not the definitive version of record of this article. This manuscript has been accepted for publication in "Journal of Molecular Endocrinology", but the version presented here has not yet been copy-edited, formatted or proofed ...
Cordido, Fernando, Diéguez, Carlos, López, Miguel, Nogueiras, Rubén, Varela, Luis, Vidal-Puig, Antonio, Vázquez, María J.   +6 more
core   +2 more sources

Growth hormone secretagogue binding sites in peripheral human tissues.

Journal of Clinical Endocrinology and Metabolism, 2000
The family of GH secretagogues (GHS) includes peptidyl (hexarelin) and nonpeptidyl (MK 0677) molecules possessing specific receptors in the brain, pituitary, and thyroid. GHS receptor subtypes have also been identified in the heart; and a gastric-derived
Mauro Papotti, C. Ghè, Paola Cassoni, F. Catapano, Romano Deghenghi, E. Ghigo, G. Muccioli   +6 more
semanticscholar   +1 more source