The Ghrelin Receptor (Ghsr) Gene Polymorphism in Indonesian Local Chicken and Crossbreed is Associated with Carcass Traits [PDF]
, 2017 Ghrelin receptor (GHSR) gene is candidate gene for growth performance in chicken by modulating growth hormone release from the pituitary by binding to its ligand of ghrelin.
Arief, I. I. (Irma) +4 more
core +2 more sources
Ghrelin receptors in non-mammalian vertebrates
Frontiers in Endocrinology, 2013 The growth hormone secretagogue-receptor (GHS-R) was discovered in humans and pigs in 1996. The endogenous ligand, ghrelin, was discovered three years later, in 1999, and our understanding of the physiological significance of the ghrelin system in ...
Hiroyuki eKaiya +2 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Somatostatin binds to a G‐protein‐coupled receptor to inhibit the release of catecholamine from chromaffin cells. This action has no impact on Ca2+ levels and is similar for Ca2+ entry through voltage‐gated Ca2 channels and for Ca2+ mobilization from the endoplasmic reticulum.
Jinbo Cheng, Meyer B. Jackson
wiley +1 more source
Ghrelin and growth hormone secretagogues (GHS): modulation of growth hormone secretion and therapeutic applications [PDF]
, 2008 Growth hormone-releasing hormone (GHRH) and somatostatin modulate growth hormone (GH) secretion. A third mechanism was discovered in the last decade, involving the action of growth hormone secretagogues (GHS).
Correa-Silva, Silvia R. +2 more
core +2 more sources
The controversial role of the vagus nerve in mediating ghrelin's actions: gut feelings and beyond
IBRO Neuroscience Reports, 2022 Ghrelin is a stomach-derived peptide hormone that acts via the growth hormone secretagogue receptor (GHSR) and displays a plethora of neuroendocrine, metabolic, autonomic and behavioral actions.
Mario Perelló +5 more
doaj
The Essentiality of Amino Acids in Healthiness and Disease State: Type II Diabetes as a Case Study
Food Science &Nutrition, Volume 13, Issue 6, June 2025.This review investigates the functions of amino acids in normal physiological states, their potential as a diagnostic biomarker, the probable risk of deficiency, and the therapeutic ability for managing and preventing type 2 diabetes mellitus. ABSTRACT A healthy life depends on the availability and the synthesis of amino acids as they are building ...
Samuel Idowu Fayomi +2 more
wiley +1 more source
LEAP2 deletion in mice enhances ghrelin's actions as an orexigen and growth hormone secretagogue
Molecular Metabolism, 2021 Kripa Shankar +12 more
semanticscholar +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.ABSTRACT Platinum‐based chemotherapeutics, particularly cisplatin, are crucial in the treatment of various malignancies due to their strong antitumor effects. However, a significant side effect of cisplatin is muscle atrophy, which severely impairs physical strength, diminishes quality of life and complicates cancer therapy.
Ko‐Chieh Huang +3 more
wiley +1 more source
Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking [PDF]
, 2015 In neurosecretory cells, secretory vesicles (SVs) undergo Ca2(+)-dependent fusion with the plasma membrane to release neurotransmitters. How SVs cross the dense mesh of the cortical actin network to reach the plasma membrane remains unclear.
Gomez, Guillermo A. +7 more
core +1 more source
Ghrelin, food intake, and botanical extracts: A Review [PDF]
Avicenna Journal of Phytomedicine, 2015 A kind of growth hormone secretagogue (GHS), ghrelin, was first isolated from the rat stomach and plays a major role in the activation of the growth hormone secretagogue receptor 1a (GHS-R1a) resulting the release of growth hormone (GH).
Peyman Rezaie +2 more
doaj