Results 121 to 130 of about 34,073 (255)

Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture

FEBS Open Bio, 2014
Low-density lipoprotein receptor (LDLR) mediates hepatic clearance of plasma cholesterol; proprotein convertase subtilisin/kexin 9 (PCSK9) opposes this clearance by promoting LDLR degradation.
Majambu Mbikay, Francine Sirois, Sonia Simoes, Janice Mayne, Michel Chrétien   +4 more
doaj   +1 more source

Purification and Characterization of Rat des-Gln14-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor*

Journal of Biological Chemistry, 2000
Ghrelin, a peptide purified from the stomach, is an endogenous ligand for the growth hormone secretagogue receptor (GHS-R) and potently stimulates growth hormone release from the pituitary. Ghrelin is modified with an n-octanoyl group at Ser3.
H. Hosoda, M. Kojima, H. Matsuo, K. Kangawa   +3 more
semanticscholar   +1 more source

The secretion of von Willebrand factor from endothelial cells; an increasingly complicated story. [PDF]

, 2013
von Willebrand factor (VWF) plays key roles in both primary and secondary hemostasis by capturing platelets and chaperoning clotting factor VIII, respectively.
Cutler, D, Nightingale, T
core   +1 more source

In vitro action of bombesin on amylase secretion, membrane potential, and membrane resistance in rat and mouse pancreatic acinar cells. A comparison with other secretagogues. [PDF]

, 1978
Naofumi Iwatsuki, Ole H. Petersen
openalex   +1 more source

Ghrelin

Molecular Metabolism, 2015
Background: The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the ...
T.D. Müller, R. Nogueiras, M.L. Andermann, Z.B. Andrews, S.D. Anker, J. Argente, R.L. Batterham, S.C. Benoit, C.Y. Bowers, F. Broglio, F.F. Casanueva, D. D'Alessio, I. Depoortere, A. Geliebter, E. Ghigo, P.A. Cole, M. Cowley, D.E. Cummings, A. Dagher, S. Diano, S.L. Dickson, C. Diéguez, R. Granata, H.J. Grill, K. Grove, K.M. Habegger, K. Heppner, M.L. Heiman, L. Holsen, B. Holst, A. Inui, J.O. Jansson, H. Kirchner, M. Korbonits, B. Laferrère, C.W. LeRoux, M. Lopez, S. Morin, M. Nakazato, R. Nass, D. Perez-Tilve, P.T. Pfluger, T.W. Schwartz, R.J. Seeley, M. Sleeman, Y. Sun, L. Sussel, J. Tong, M.O. Thorner, A.J. van der Lely, L.H.T. van der Ploeg, J.M. Zigman, M. Kojima, K. Kangawa, R.G. Smith, T. Horvath, M.H. Tschöp   +56 more
doaj   +1 more source

Growth Hormone Secretagogue Treatment in Hypogonadal Men Raises Serum Insulin-Like Growth Factor-1 Levels

American Journal of Men's Health, 2017
Realizing the reported misuse of human growth hormone (GH), investigation of a safe alternative mechanism for increasing endogenous GH is needed. Several GH secretagogues are available, including GH-releasing peptides (GHRPs) GHRP-2 and GHRP-6, and the ...
John T. Sigalos, Alexander W. Pastuszak, Andrew Allison, Samuel J. Ohlander, Amin Herati, Mark C. Lindgren, Larry I. Lipshultz   +6 more
doaj   +1 more source

Impact of level 2 hypoglycaemia on neuroaxonal damage biomarker in individuals with type 2 diabetes: A stepwise hypoglycaemic clamp study

Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 3519-3522, June 2025.
Harald Sourij, Kehkishan Azhar, Felix Aberer, Caren Sourij, Norbert J. Tripolt, Harald Kojzar, Peter N. Pferschy, Arabella Buchmann, Faisal Aziz, Michael Khalil   +9 more
wiley   +1 more source

Ghrelin; The Renown Hormone [PDF]

, 2006
Ghrelin , a 28 amino acid gastric peptide, was found to be a potent releaser of GH and in addition, actively participate in controlling energy balance and the regulation of food intake. Specifically, plasma ghrelin originates in the oxyntic gland where A-
H. Murat Bilgin
core  

Spatial redistribution of neurosecretory vesicles upon stimulation accelerates their directed transport to the plasma membrane

PLoS ONE, 2022
Through the integration of results from an imaging analysis of intracellular trafficking of labelled neurosecretory vesicles in chromaffin cells, we develop a Markov state model to describe their transport and binding kinetics.
Elaine B. Schenk, Frederic A. Meunier, Dietmar B. Oelz   +2 more
doaj  

A G‐protein mediates secretagogue‐induced gap junctional channel closure in pancreatic acinar cells [PDF]

, 1989
Roland Somogyi, Hans‐Albert Kolb
openalex   +1 more source