Results 121 to 130 of about 34,970 (301)

Induction of Secretagogue Independent Gastric Acid Secretion via a Novel Aspirin-Activated Pathway

open access: yesFrontiers in Physiology, 2019
Aspirin has been widely recommended for acute and chronic conditions for over 2,000 years. Either single or repetitive doses are commonly used for analgesic and antipyretic reasons and to prevent heart attacks, stroke, and blood clot formation.
Alice Miriam Kitay   +5 more
doaj   +1 more source

Characterization of blood-derived exosomal proteins after exercise

open access: yesJournal of International Medical Research, 2020
Objective To assess changes in plasma exosome levels and protein content in mice after long-term exercise. Methods We subjected 9-month-old adult C57BL/6J mice to daily treadmill running exercise for 4 weeks prior to the isolation of blood-derived ...
Hongkai Xiang   +5 more
doaj   +1 more source

The secretion of von Willebrand factor from endothelial cells; an increasingly complicated story. [PDF]

open access: yes, 2013
von Willebrand factor (VWF) plays key roles in both primary and secondary hemostasis by capturing platelets and chaperoning clotting factor VIII, respectively.
Cutler, D, Nightingale, T
core   +1 more source

The Structural Basis for the Binding of Repaglinide to the Pancreatic KATP Channel

open access: yesCell Reports, 2019
Summary: Repaglinide (RPG) is a short-acting insulin secretagogue widely prescribed for the treatment of type 2 diabetes. It boosts insulin secretion by inhibiting the pancreatic ATP-sensitive potassium channel (KATP).
Dian Ding   +4 more
doaj  

Carnosine scavenging of glucolipotoxic free radicals enhances insulin secretion and glucose uptake [PDF]

open access: yes, 2017
The worldwide prevalence of diabetes has risen to 8.5% among adults, which represents a staggering rise in prevalence from 4.7% in 1980. Whilst some treatments work by increasing insulin secretion, over time their effectiveness decreases.
B Courten de   +20 more
core   +2 more sources

Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2002
Ghrelin is a novel gastrointestinal hormone produced by rat and human gastric X-like neuroendocrine cells, which strongly stimulates GH secretion and influences energy balance, gastric motility, and acid secretion.
M. Volante   +8 more
semanticscholar   +1 more source

Apo-ghrelin receptor (apo-GHSR1a) Regulates Dopamine Signaling in the Brain

open access: yesFrontiers in Endocrinology, 2014
The orexigenic peptide hormone ghrelin is synthesized in the stomach and its receptor growth hormone secretagogue receptor (GHSR1a) is expressed mainly in the central nervous system (CNS).
Andras eKern   +2 more
doaj   +1 more source

Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture

open access: yesFEBS Open Bio, 2014
Low-density lipoprotein receptor (LDLR) mediates hepatic clearance of plasma cholesterol; proprotein convertase subtilisin/kexin 9 (PCSK9) opposes this clearance by promoting LDLR degradation.
Majambu Mbikay   +4 more
doaj   +1 more source

Amino Acids as Gastric Secretagogues

open access: yesExperimental Biology and Medicine, 1933
In the course of our recent studies on the secretion of gastric pepsin, we examined the effects of small amounts of amino-acids administered by the technique of Tagawa1 to Pavlov gastric pouch dogs. The volumes of juice obtained were too small to allow accurate calculations of the total pepsin contents to be made, and the volume of secretion obtained ...
George R. Cowgill, Elizabeth R. B. Smith
openaire   +2 more sources

The expression of the growth hormone secretagogue receptor ligand ghrelin in normal and abnormal human pituitary and other neuroendocrine tumors.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2001
Ghrelin is a recently identified endogenous ligand of the GH secretagogue (GHS) receptor. It was originally isolated from the stomach, but has also been shown to be present in the rat hypothalamus.
M. Korbonits   +7 more
semanticscholar   +1 more source

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