Apo-ghrelin receptor (apo-GHSR1a) Regulates Dopamine Signaling in the Brain
The orexigenic peptide hormone ghrelin is synthesized in the stomach and its receptor growth hormone secretagogue receptor (GHSR1a) is expressed mainly in the central nervous system (CNS).
Andras eKern +2 more
doaj +1 more source
Supplementary Figure S1A-C from The Neuromedin U-Growth Hormone Secretagogue Receptor 1b/Neurotensin Receptor 1 Oncogenic Signaling Pathway as a Therapeutic Target for Lung Cancer [PDF]
Koji Takahashi +14 more
openalex +1 more source
Growth hormone secretagogues modulate inflammation and fibrosis in mdx mouse model of Duchenne muscular dystrophy [PDF]
Brigida Boccanegra +20 more
openalex +1 more source
TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced Diarrhea [PDF]
Hannah R. Wardill +7 more
openalex +1 more source
Gαs defines the fundamental coupling mechanism of insulin secretion
Journal of Diabetes Investigation, Volume 17, Issue 1, Page 9-11, January 2026.
Jun Shirakawa
wiley +1 more source
Background: The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the ...
T.D. Müller +56 more
doaj +1 more source
L163,255, a Synthetic Growth Hormone Secretagogue, Raises [Ca2+]i by Promoting Intracellular Calcium Stores Depletion in Intact Fast-Twitch Fibers of Rat Skeletal Muscle [PDF]
Antonella Liantonio +3 more
openalex +1 more source
The effect of intravenous injection of Ghrelin on the mean plasma concentrations of insulin in immature camels fed different levels of their energy requirements [PDF]
Ghrelin is a peptide hormone secreted into the circulation from the stomach, but this peptide is also synthetized in a number of different body tissues including the brain and pancreas, suggesting both endocrine and paracrine effects.
doaj
Through the integration of results from an imaging analysis of intracellular trafficking of labelled neurosecretory vesicles in chromaffin cells, we develop a Markov state model to describe their transport and binding kinetics.
Elaine B. Schenk +2 more
doaj
Realizing the reported misuse of human growth hormone (GH), investigation of a safe alternative mechanism for increasing endogenous GH is needed. Several GH secretagogues are available, including GH-releasing peptides (GHRPs) GHRP-2 and GHRP-6, and the ...
John T. Sigalos +6 more
doaj +1 more source

