Results 81 to 90 of about 34,970 (301)

Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor.

Endocrinology, 2004
Ghrelin promotes fat accumulation, despite potent stimulation of the lipolytic hormone, GH. The function of the major circulating isoform of ghrelin, des-octanoyl ghrelin, is unclear, because it does not activate the GH secretagogue receptor (GHS-R1a ...
N. Thompson, Dave A S Gill, R. Davies, N. Loveridge, P. Houston, I. Robinson, T. Wells   +6 more
semanticscholar   +1 more source

Functional, Nutraceutical and Health Endorsing Perspectives of Saffron

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Saffron is generally regarded as safe for human consumption in moderate quantities, its potential adverse effects at higher doses require careful consideration. This review presents a balanced perspective on saffron's medicinal potential and its safe usage, making it a valuable resource for researchers and healthcare professionals.
Tabussam Tufail, Huma Badr ul Ain, Ali Ikram, Muhammad Tayyab Arshad, Muhammed Adem Abdullahi   +4 more
wiley   +1 more source

Identification and characterisation of enteroaggregative Escherichia coli subtypes associated with human disease [PDF]

, 2020
Enteroaggregative E. coli (EAEC) are a major cause of diarrhoea worldwide. Due to their heterogeneity and carriage in healthy individuals, identification of diagnostic virulence markers for pathogenic strains has been difficult.
Brett, Bernard, Bundy, Leah, Chattaway, Marie A., Crossman, Lisa C., Ellis, Samuel J., Hölken, Johanna M., Kay, Gemma L., McGrath, Conor J., Schüller, Stephanie, Wain, John   +9 more
core   +1 more source

Nutritional priorities to support GLP‐1 therapy for obesity: A joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society

Obesity, Volume 33, Issue 8, Page 1475-1503, August 2025.
Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian, Monica Agarwal, Monica Aggarwal, Lydia Alexander, Caroline M. Apovian, Shagun Bindlish, Jonathan Bonnet, W. Scott Butsch, Sandra Christensen, Eugenia Gianos, Mahima Gulati, Alka Gupta, Debbie Horn, Ryan M. Kane, Jasdeep Saluja, Deepa Sannidhi, Fatima Cody Stanford, Emily A. Callahan   +17 more
wiley   +1 more source

The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion

eLife
Life histories of oviparous species dictate high metabolic investment in the process of gonadal development leading to ovulation. In vertebrates, these two distinct processes are controlled by the gonadotropins follicle-stimulating hormone (FSH) and ...
Lian Hollander-Cohen, Omer Cohen, Miriam Shulman, Tomer Aiznkot, Pierre Fontanaud, Omer Revah, Patrice Mollard, Matan Golan, Berta Levavi-Sivan   +8 more
doaj   +1 more source

The Ghrelin Receptor (Ghsr) Gene Polymorphism in Indonesian Local Chicken and Crossbreed is Associated with Carcass Traits [PDF]

, 2017
Ghrelin receptor (GHSR) gene is candidate gene for growth performance in chicken by modulating growth hormone release from the pituitary by binding to its ligand of ghrelin.
Arief, I. I. (Irma), Budiman, C. (Cahyo), Jakaria, J. (Jakaria), Khaerunnisa, I. (Isyana), Sumantri, C. (Cece)   +4 more
core   +2 more sources

Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.

Endocrinology, 2006
Ghrelin, an acylated peptide produced predominantly in the stomach, stimulates feeding and GH secretion via interactions with the GH secretagogue type 1a receptor (GHS-R1a), the functionally active form of the GHS-R.
K. Toshinai, H. Yamaguchi, Yuxiang Sun, Roy G. Smith, A. Yamanaka, T. Sakurai, Y. Date, M. S. Mondal, T. Shimbara, Takashi Kawagoe, N. Murakami, M. Miyazato, K. Kangawa, M. Nakazato   +13 more
semanticscholar   +1 more source

An INS‐1 832/13 𝛽‐Cell Proteome Highlights the Rapid Regulation of Fatty Acid Biosynthesis in Glucose‐Stimulated Insulin Secretion

PROTEOMICS, Volume 25, Issue 15, Page 13-26, August 2025.
ABSTRACT Pancreatic beta cells secrete insulin in response to rising glucose levels, a process known as glucose‐stimulated insulin secretion (GSIS). Here, we acquire proteomes of rat pancreatic INS‐1 832/13 beta cells that were short‐term stimulated with 11 different glucose concentrations from 0 to 20 mM, quantifying the response of 3703 proteins ...
Nina Stremmel, Oliver Lemke, Kathrin Textoris‐Taube, Daniela Ludwig, Michael Mülleder, Julia Muenzner, Markus Ralser   +6 more
wiley   +1 more source

Protective effects of urocortin 2 against caerulein-induced acute pancreatitis. [PDF]

, 2019
Because little is known about the role of corticotropin-releasing factor (CRF) agonists in regulating responses in pancreatitis, we evaluated the effects of urocortin 2 (UCN2) and stressin1 in caerulein-induced acute pancreatitis (AP) model in rats. Male
Bhargava, Aditi, Chheda, Chintan, Hasdemir, Burcu, Pandol, Stephen J, Rivier, Jean, Tan, Tanya, Yuan, Jingzhen   +6 more
core   +1 more source

Calcium-sensing receptor inhibits secretagogue-induced electrolyte secretion by intestine via the enteric nervous system.

American Journal of Physiology - Gastrointestinal and Liver Physiology, 2012
Bacterial toxins such as cholera toxin induce diarrhea by both direct epithelial cell generation of cyclic nucleotides as well as stimulation of the enteric nervous system (ENS).
Sam X. Cheng
semanticscholar   +1 more source