Results 111 to 120 of about 34,649 (253)

The Interplay between Hormones and Irritable Bowel Disease [PDF]

open access: yes, 2013
Thesis (M.A.)--Boston UniversityThis thesis examines the underlying mechanisms causing the severe and often debilitating symptoms associated with both Irritable Bowel Syndrome and Inflammatory Bowel Disease.
Linson, Elyse A.
core   +1 more source

Structural and functional divergence of growth hormone-releasing hormone receptors in early sarcopterygians: lungfish and Xenopus [PDF]

open access: yes, 2013
The evolutionary trajectories of growth hormone-releasing hormone (GHRH) receptor remain enigmatic since the discovery of physiologically functional GHRH-GHRH receptor (GHRHR) in non-mammalian vertebrates in 2007.
Chow, BKC, Lee, TO, TAM, KV
core   +1 more source

Synthetic Peptides as Therapeutic Agents: Lessons Learned From Evolutionary Ancient Peptides and Their Transit Across Blood-Brain Barriers

open access: yesFrontiers in Endocrinology, 2019
Peptides play a major role in the transmission of information to and from the central nervous system. However, because of their structural complexity, the development of pharmacological peptide-based therapeutics has been challenged by the lack of ...
David A. Lovejoy   +8 more
doaj   +1 more source

Structural and functional insights into the pilotin-secretin complex of the type II secretion system.

open access: yesPLoS Pathogens, 2012
Gram-negative bacteria secrete virulence factors and assemble fibre structures on their cell surface using specialized secretion systems. Three of these, T2SS, T3SS and T4PS, are characterized by large outer membrane channels formed by proteins called ...
Shuang Gu   +4 more
doaj   +1 more source

Exocrine Pancreatic Function Tests: A Review

open access: yesCanadian Journal of Gastroenterology, 1989
Exocrine pancreatic function tests (PFTs) remain of value in the diagnosis and assessment of chronic pancreatic disease. Direct intubation PFTs, using secretin/cholecystokinin or secretin/caerulein as the stimulants, continue to the the 'gold standard ...
Yuyuan Li   +2 more
doaj   +1 more source

Stages of chronic pancreatitis development

open access: yesТерапевтический архив, 2011
Aim. To ascertain correlations between pancreatic secretion disturbances and stage and complications of chronic pancreatitis (CP). Material and methods. The examination covered 81 CP patients (32 females, 49 males, mean age 55.9±1.8 years).
Lyudmila Vasil'evna Vinokurova   +5 more
doaj  

Influence of high-dose pancreatic enzyme treatment on pancreatic function in healthy volunteers [PDF]

open access: yes, 2018
Summary: Conclusions. Adaptive changes in exocrine and endocrine pancreatic function, as well as changes in pancreas size and morphology, were not observed after 4 wk of oral pancreatic enzyme application.
Büchler, Markus   +5 more
core  

Exceptionally widespread nanomachines composed of type IV pilins: the prokaryotic Swiss Army knives

open access: yes, 2014
Prokaryotes have engineered sophisticated surface nanomachines that have allowed them to colonize Earth and thrive even in extreme environments. Filamentous machineries composed of type IV pilins, which are associated with an amazing array of properties ...
Berry, J-L, Pelicic, V
core   +3 more sources

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