Type VI secretion: a beginner's guide [PDF]
Type VI secretion is a newly described mechanism for protein transport across the cell envelope of Gram-negative bacteria. Components that have been partially characterised include an IcmF homologue, the ATPase ClpV, a regulatory FHA domain protein and ...
Akeda+47 more
core +1 more source
The Role of Bile in the Regulation of Exocrine Pancreatic Secretion [PDF]
As early as 1926 Mellanby (1) was able to show that introduction of bile into the duodenum of anesthetized cats produces a copious flow of pancreatic juice.
Adamczyk W+75 more
core +1 more source
Cystic fibrosis (CF) is the most common genetic disorder that causes a significant damage in secretory epithelial cells due to the defective ion flux across the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel.
Tamara Madácsy+5 more
doaj +1 more source
Synaptotagmin-1 is the Ca2+ sensor for fast striatal dopamine release
Dopamine powerfully controls neural circuits through neuromodulation. In the vertebrate striatum, dopamine adjusts cellular functions to regulate behaviors across broad time scales, but how the dopamine secretory system is built to support fast and slow ...
Aditi Banerjee+4 more
doaj +1 more source
Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells. [PDF]
Glucagon is one of the main regulators of blood glucose levels and dysfunctional stimulus secretion coupling in pancreatic A-cells is believed to be an important factor during development of diabetes.
Ahlstedt, I.+3 more
core +1 more source
Persistent DNA damage signaling triggers senescence-associated inflammatory cytokine secretion
Cellular senescence suppresses cancer by stably arresting the proliferation of damaged cells. Paradoxically, senescent cells also secrete factors that alter tissue microenvironments. The pathways regulating this secretion are unknown.
F. Rodier+9 more
semanticscholar +1 more source
Ex vivo innate immune cytokine signature of enhanced risk of relapsing brucellosis. [PDF]
BackgroundBrucellosis, a zoonotic infection caused by one of the Gram-negative intracellular bacteria of the Brucella genus, is an ongoing public health problem in Perú.
Feldman, Kristyn E+9 more
core +3 more sources
Development of an improved Pseudoalteromonas haloplanktis TAC125 strain for recombinant protein secretion at low temperature [PDF]
Background: In a previous paper, we reported the accomplishment of a cold gene-expression system for the recombinant secretion of heterologous proteins in Pseudoalteromonas haloplanktis TAC125.
CIRULLI C.+3 more
core +1 more source
Genomic Analysis of ATP Efflux in Saccharomyces cerevisiae
Adenosine triphosphate (ATP) plays an important role as a primary molecule for the transfer of chemical energy to drive biological processes. ATP also functions as an extracellular signaling molecule in a diverse array of eukaryotic taxa in a conserved ...
Theodore W. Peters+5 more
doaj +1 more source
Influence of microclimatic conditions on nectar exudation in Glechoma hirsuta W. K [PDF]
The nectar production of Glechoma hirsuta W. K. grown under different microclimatic habitat conditions was evaluated by determining the total daily nectar quantity per flower, diurnal dynamics of nectar secretion, the nectar secretion rate, and sugar ...
Mačukanović-Jocić Marina+1 more
doaj +1 more source