Results 31 to 40 of about 2,802,374 (388)

Persistent DNA damage signaling triggers senescence-associated inflammatory cytokine secretion

open access: yesNature Cell Biology, 2009
Cellular senescence suppresses cancer by stably arresting the proliferation of damaged cells. Paradoxically, senescent cells also secrete factors that alter tissue microenvironments. The pathways regulating this secretion are unknown.
F. Rodier   +9 more
semanticscholar   +1 more source

Abdominal functional electrical stimulation to enhance mechanical insufflation-exsufflation [PDF]

open access: yes, 2015
Context: Respiratory complications, attributed to the build-up of secretions in the airway, are a leading cause of rehospitalisation for the tetraplegic population.
Allan, David B.   +3 more
core   +1 more source

Cystic Fibrosis of the Pancreas: The Role of CFTR Channel in the Regulation of Intracellular Ca2+ Signaling and Mitochondrial Function in the Exocrine Pancreas

open access: yesFrontiers in Physiology, 2018
Cystic fibrosis (CF) is the most common genetic disorder that causes a significant damage in secretory epithelial cells due to the defective ion flux across the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel.
Tamara Madácsy   +5 more
doaj   +1 more source

Permissible Secrets [PDF]

open access: yesThe Philosophical Quarterly, 2017
This article offers an account of the information condition on morally valid consent in the context of sexual relations. The account is grounded in rights. It holds that a person has a sufficient amount of information to give morally valid consent if, and only if, she has all the information to which she has a claim-right. A person has a claim-right to
Lazenby, Hugh, Gabriel, Iason
openaire   +2 more sources

An investigation into the relationship between small intestinal fluid secretion and systemic arterial blood pressure in the anesthetized rat [PDF]

open access: yes, 2015
In the absence of an ability to absorb fluid by cellular uptake mechanisms, fluid movement in vivo from the perfused rat intestine is absorptive when the diastolic blood pressure is normal or very low but is secretory when blood pressure falls below ...
Lucas, Michael, Morrison, James
core   +1 more source

Revealing the secrets of secretion

open access: yeseLife, 2018
An intracellular ion channel may have a central role in the release of cytokines by macrophages.
Antony Galione, Lianne C Davis
openaire   +3 more sources

A novel platform for the production of nonhydroxylated gelatins based on the methylotrophic yeast Hansenula polymorpha [PDF]

open access: yes, 2007
The use of yeast as a host for heterologous expression of proteins that are normally derived from animal tissue is a promising way to ensure defined products that are devoid of potential harmful animal side products.
Boer, Arjo L. de,   +4 more
core   +2 more sources

Comparative analysis of canine mesenchymal stem cells and bone marrow-derived mononuclear cells [PDF]

open access: yesVeterinary World, 2021
Background and Aim: Mesenchymal stem cells (MSCs), which have multi-lineage differentiation potentials, are a promising source for regenerative medicine.
Noritaka Maeta   +3 more
doaj   +1 more source

Insulin-like growth factor-1 is a negative modulator of glucagon secretion [PDF]

open access: yes, 2017
Glucagon secretion involves a combination of paracrine, autocrine, hormonal, and autonomic neural mechanisms. Type 2 diabetes often presents impaired glucagon suppression by insulin and glucose.
Andreozzi, F   +6 more
core   +1 more source

Efficient Autotransporter-Mediated Extracellular Secretion of a Heterologous Recombinant Protein by Escherichia coli

open access: yesMicrobiology Spectrum, 2023
The autotransporter protein secretion system has been used previously to target the secretion of heterologous proteins to the bacterial cell surface and the extracellular milieu at the laboratory scale.
Irene Beriotto   +12 more
doaj   +1 more source

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