Results 71 to 80 of about 1,632,786 (366)

Microreview: type IV secretion systems: versatility and diversity in function

, 2010
Type IV secretion systems (T4SSs) are large protein complexes which traverse the cell envelope of many bacteria. They contain a channel through which proteins or protein–DNA complexes can be translocated.
Angel Rivera-Calzada, Walldén, Karin, Waksman, Gabriel, Rivera-Calzada, A., Karin Wallden, Gabriel Waksman   +5 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Effect of Intraduodenal Bile and Na-Taurodeoxycholate on Exocrine Pancreatic Secretion and on Plasma Levels of Secretin, Pancreatic Polypeptide, and Gastrin in Man [PDF]

, 1990
The effect of intraduodenally administered cattle bile (CB) and Na-taurodeoxycholate (TDC) on basal pancreatic secretion and plasma levels of secretin, pancreatic polypeptide (PP), and gastrin were investigated on two separate days in 10 fasting ...
Fiedler, F., Teufel, Johannes, Riepl, Rudolf L., Burhol, P. G., Scharl, A., Lehnert, Peter, Hempen, I.   +6 more
core   +1 more source

Response of the tegument of Fasciola hepatica to infection and immunization sera in vitro

Parasitology
The migratory phase is a critical time for Fasciola hepatica as it must locate, penetrate and migrate through the alimentary tract to the liver parenchyma whilst under attack from the host immune response.
Clive E. Bennett, Adam P.S. Bennett, Robert E.B. Hanna, Mark W. Robinson   +3 more
doaj   +1 more source

The structure of some floral elements and the nectar production rate of Polemonium caeruleum L.

Acta Agrobotanica, 2012
The present study, carried out in the period 2008 - 2009, covered some morphological and anatomical features of the flowers of Polemonium caeruleum L. and their nectar production rate in the climatic conditions of the Lublin region.
Mirosława Chwil
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

The role of TcdB and TccC subunits in secretion of the photorhabdus Tcd toxin complex [PDF]

, 2013
The Toxin Complex (TC) is a large multi-subunit toxin encoded by a range of bacterial pathogens. The best-characterized examples are from the insect pathogens Photorhabdus, Xenorhabdus and Yersinia.
Guowei Yang, Yang Guowei, Yang, Guowei, Guowei Yang (163967), Waterfield, Nicholas R., Nicholas R. Waterfield (163985), Nicholas R Waterfield, Waterfield Nicholas R.   +7 more
core   +1 more source

Extracellular proteins: Novel key components of metal resistance in cyanobacteria?

Frontiers in Microbiology, 2016
Metals are essential for all living organisms and required for fundamental biochemical processes. However, when in excess, metals can turn into highly-toxic agents able to disrupt cell membranes, alter enzymatic activities and damage DNA.
Joaquin eGiner-Lamia, Joaquin eGiner-Lamia, Sara Bernardes Pereira, Sara Bernardes Pereira, Miquel eBovea-Marco, Matthias Erwin Futschik, Matthias Erwin Futschik, Paula eTamagnini, Paula eTamagnini, Paula eTamagnini, Paulo eOliveira, Paulo eOliveira   +11 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Global transcriptional profiling of Burkholderia pseudomallei under salt stress reveals differential effects on the Bsa type III secretion system. [PDF]

, 2010
BACKGROUND: Burkholderia pseudomallei is the causative agent of melioidosis where the highest reported incidence world wide is in the Northeast of Thailand, where saline soil and water are prevalent.
Stabler, Richard A., Sunee Korbsrisate, Stevens, Mark P, Pornpan Pumirat, Ekapot Singsuksawat, Wren, Brendan W, Korbsrisate, Sunee, Singsuksawat, Ekapot, Mark P Stevens, Muangsombut, Veerachat, Veerachat Muangsombut, Cuccui, Jon, Richard A Stabler, Joanne M Stevens, Pumirat, Pornpan, Wren, Brendan W., Stabler, Richard A, Stevens, Joanne M, Stevens, Joanne M.; id_orcid, Stevens, Mark P., Jon Cuccui, Brendan W Wren   +21 more
core   +1 more source