Results 11 to 20 of about 61,645 (272)
The nanostructured secretome [PDF]
Biomaterials Science, 2020 The term secretome should be expanded to also include the great variety of nanoparticles secreted by cells into the extracellular space, which ranges from lipoproteins of a few nanometers to extracellular vesicles of hundreds of nanometers.
Busatto, S +6 more
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Targeting the mutant p53 secretome [PDF]
Journal of Clinical Investigation, 2021 While p53 is the most highly mutated and perhaps best studied tumor suppressor protein related to cancer, it remains refractory to targeted therapeutic strategies. In this issue of the JCI, Tan and colleagues investigated the mechanistic basis of the mutant p53 secretome in preclinical models of lung adenocarcinoma.
Kartik Sehgal, David A. Barbie
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Science Signaling, 2019 A database provides information on the relative abundances and locations of human proteins that are predicted to be secreted.
Mathias Uhlén +52 more
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Proteomic Profiling of the Human Fetal Multipotent Mesenchymal Stromal Cells Secretome
Molecules, 2020 Secretome of multipotent mesenchymal stromal cells (MSCs) is actively used in biomedical applications such as alveolar bone regeneration, treatment of cardiovascular disease, and neurodegenerative disorders.
Arseniy A. Lobov +6 more
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In Vitro Assessment of Cytokine Expression Profile of MCF-7 Cells in Response to hWJ-MSCs Secretome [PDF]
Advanced Pharmaceutical Bulletin, 2019 Purpose: Several attempts have been made to identify the mechanisms by which mesenchymal stem cells (MSCs)-derived secretome exert anti-tumor or tumorigenic effects, but still further investigations are needed to explore this subject. Thus, in this study
Mansoureh Mirabdollahi +2 more
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Adipose Mesenchymal Stem Cell Secretome Modulated in Hypoxia for Remodeling of Radiation-Induced Salivary Gland Damage. [PDF]
PLoS ONE, 2015 This study was conducted to determine whether a secretome from mesenchymal stem cells (MSC) modulated by hypoxic conditions to contain therapeutic factors contributes to salivary gland (SG) tissue remodeling and has the potential to improve irradiation ...
Hye-Young An +5 more
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Metabolites, 2023 According to studies, the microbiome may contribute to the emergence and spread of breast cancer. E. coli is one of the Enterobacteriaceae family recently found to be present as part of the breast tissue microbiota.
Reem H. AlMalki +7 more
doaj +1 more source
Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions [PDF]
, 2016 Babesia microti, a tick-transmitted, intraerythrocytic protozoan parasite circulating mainly among small mammals, is the primary cause of human babesiosis.
Ben Mamoun, Choukri +31 more
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Cellular interactions in the tumor microenvironment: the role of secretome [PDF]
, 2019 Over the past years, it has become evident that cancer initiation and progression depends on several components of the tumor microenvironment, including inflammatory and immune cells, fibroblasts, endothelial cells, adipocytes, and extracellular matrix ...
Castelo-Branco, Pedro +6 more
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Fungal Secretome Database: Integrated platform for annotation of fungal secretomes [PDF]
BMC Genomics, 2010 Abstract Background Fungi secrete various proteins that have diverse functions. Prediction of secretory proteins using only one program is unsatisfactory. To enhance prediction accuracy, we constructed Fungal Secretome Database (FSD). Description A three-layer hierarchical
Park Jongsun +5 more
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