Results 41 to 50 of about 44,866 (298)

Hypoxia Mesenchymal Stem Cells-Derived Exosomes Suppress IL-5 and STAT3 Gene Expression in a Calcipotriol-Induced Atopic Dermatitis Mouse Model

open access: yesJournal of Tropical Pharmacy and Chemistry
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by Th2-mediated immune dysregulation and activation of inflammatory signaling pathways. Hypoxia mesenchymal stem cells-derived exosomes (EH-MSCs) have emerged as a promising cell-
Salindri Prawitasari   +4 more
doaj   +1 more source

Comparative Analysis of Adipose-Derived Stromal Cells and Their Secretome for Auricular Cartilage Regeneration

open access: yesStem Cells International, 2020
Adipose-derived stromal cells (ADSCs) can repair auricular cartilage defects. Furthermore, stem cell secretome may also be a promising biological therapeutic option, which is equal to or even superior to the stem cell.
Se-Joon Oh   +6 more
doaj   +1 more source

Secretome-based proteomics reveals sulindac-modulated proteins released from colon cancer cells

open access: yes, 2009
Although experiments in rodents and human population-based studies have demonstrated the efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) such as sulindac in colorectal cancer (CRC) prevention, a detailed knowledge of the underlying mechanism of
Richard Simpson (9487685)   +4 more
core   +1 more source

miRNA profiling of MSC secretome

open access: yes, 2023
miRNA profiling data from MSC secretome using NanoString ...
Dwi Aris Agung Nugrahaningsih (11113491)   +1 more
core   +1 more source

The secretome of Campylobacter concisus [PDF]

open access: yesThe FEBS Journal, 2010
A higher prevalence of Campylobacter concisus and higher levels of IgG antibodies specific to C. concisus in Crohn’s disease patients than in controls were recently detected. In this study, 1D and 2D gel electrophoresis coupled with LTQ FT‐MS and QStar tandem MS, respectively, were performed to characterize the secretome of a C.
Nadeem O, Kaakoush   +6 more
openaire   +2 more sources

HCSD: the human cancer secretome database [PDF]

open access: yes, 2015
The human cancer secretome database (HCSD) is a comprehensive database for human cancer secretome data. The cancer secretome describes proteins secreted by cancer cells and structuring information about the cancer secretome will enable further analysis ...
Amir Feizi   +11 more
core   +1 more source

Secretome-Based Prediction of Three-Dimensional Hepatic Microtissue Physiological Relevance

open access: yes, 2019
Early biomarkers for indication of the complex physiological relevance (CPR) of a three-dimensional (3D) tissue model are needed. CPR is detected late in culture and requires different analytical techniques.
Megan Douglass (8101253)   +4 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira   +8 more
wiley   +1 more source

The Zebrafish Secretome

open access: yesZebrafish, 2008
The secretome is a functionally rich proteome subset, including cellular membrane and extracellular proteins processed through the secretory pathway. In this study, Danio rerio and Homo sapiens RefSeq proteins were analyzed with SignalP, TargetP, Phobius, and pTarget algorithms.
openaire   +3 more sources

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