Results 41 to 50 of about 46,674 (254)
Pharmaceutics, 2021 Multipotent mesenchymal stromal cells (MSCs) are considered to be critical contributors to injured tissue repair and regeneration, and MSC-based therapeutic approaches have been applied to many peripheral and central neurologic disorders.
Maxim Karagyaur +10 more
doaj +1 more source
Secretome-Based Prediction of Three-Dimensional Hepatic Microtissue Physiological Relevance
, 2019 Early biomarkers for indication of the complex physiological relevance (CPR) of a three-dimensional (3D) tissue model are needed. CPR is detected late in culture and requires different analytical techniques.
Megan Douglass (8101253) +4 more
core +1 more source
Cell Secretome: Basic Insights and Therapeutic Opportunities for CNS Disorders
Pharmaceuticals, 2020 Transplantation of stem cells, in particular mesenchymal stem cells (MSCs), stands as a promising therapy for trauma, stroke or neurodegenerative conditions such as spinal cord or traumatic brain injuries (SCI or TBI), ischemic stroke (IS), or Parkinson&#
Andreia G. Pinho +4 more
doaj +1 more source
[Secretome: definitions and biomedical interest]
, 2008 International audienceINTRODUCTION: The secretome, or secretomics refers to the global study of proteins that are secreted by a cell, a tissue or an organism.
Chenau, Jérôme +2 more
core +1 more source
Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction
Advanced Materials, EarlyView.The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu +2 more
wiley +1 more source
Stem Cells International, 2020 Adipose-derived stromal cells (ADSCs) can repair auricular cartilage defects. Furthermore, stem cell secretome may also be a promising biological therapeutic option, which is equal to or even superior to the stem cell.
Se-Joon Oh +6 more
doaj +1 more source
Inter-species platelet secretome comparisons.
, 2019 Inter-species platelet secretome comparisons.
Signe E. Cremer (7861373) +5 more
core +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Cell Secretome from Mesenchymal Stem Cells for Periodontal Regeneration [PDF]
Periodontitis affects approximately 50% of the global adult population and results in varying degrees of periodontal destruction. The regeneration of periodontal tissue is in great demand but is currently difficult to achieve.
Zhang, Xiaoxin +5 more
core +1 more source
Advanced Science, EarlyView.The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang +11 more
wiley +1 more source