Results 31 to 40 of about 46,674 (254)

In Vitro Assessment of Cytokine Expression Profile of MCF-7 Cells in Response to hWJ-MSCs Secretome [PDF]

Advanced Pharmaceutical Bulletin, 2019
Purpose: Several attempts have been made to identify the mechanisms by which mesenchymal stem cells (MSCs)-derived secretome exert anti-tumor or tumorigenic effects, but still further investigations are needed to explore this subject. Thus, in this study
Mansoureh Mirabdollahi, Shaghayegh Haghjooy Javanmard, Hojjat Sadeghi-Aliabadi   +2 more
doaj   +1 more source

Metabolic Alteration of MCF-7 Cells upon Indirect Exposure to E. coli Secretome: A Model of Studying the Microbiota Effect on Human Breast Tissue

Metabolites, 2023
According to studies, the microbiome may contribute to the emergence and spread of breast cancer. E. coli is one of the Enterobacteriaceae family recently found to be present as part of the breast tissue microbiota.
Reem H. AlMalki, Malak A. Jaber, Mysoon M. Al-Ansari, Khalid M. Sumaily, Monther Al-Alwan, Essa M. Sabi, Abeer K. Malkawi, Anas M. Abdel Rahman   +7 more
doaj   +1 more source

Secretome Proteomic Approaches for Biomarker Discovery: An Update on Colorectal Cancer

Medicina, 2020
Searching for new cancer-related biomarkers is a key priority for the early detection of solid tumors, such as colorectal cancer (CRC), in clinically relevant biological fluids.
Armando Cevenini, Stefania Orrù, Esther Imperlini   +2 more
doaj   +1 more source

Stem cell secretome derived from human amniotic fluid affords neuroprotection in an ischemic model

Brain Circulation, 2021
Human amniotic fluid stem cells (hAFSCs) are growing in interest; yet, little is understood about their secretome and neuroprotective actions in different diseases, including stroke.
Chase Kingsbury, Liborio Stuppia
doaj   +1 more source

Adipose Mesenchymal Extracellular Vesicles as Alpha-1-Antitrypsin Physiological Delivery Systems for Lung Regeneration

Cells, 2019
Accumulating evidence shows that Mesenchymal Stem/Stromal Cells (MSCs) exert their therapeutic effects by the release of secretome, made of both soluble proteins and nano/microstructured extracellular vesicles (EVs).
Elia Bari, Ilaria Ferrarotti, Dario Di Silvestre, Pietro Grisoli, Valentina Barzon, Alice Balderacchi, Maria Luisa Torre, Rossana Rossi, Pierluigi Mauri, Angelo Guido Corsico, Sara Perteghella   +10 more
doaj   +1 more source

The human secretome [PDF]

, 2019
The proteins secreted by human cells (collectively referred to as the secretome) are important not only for the basic understanding of human biology but also for the identification of potential targets for future diagnostics and therapies.
Tegel, Hanna,, Kanje, Sara, Hober, Andreas, Bergstrom, Goran,, Fagerberg, Linn, Hober, Andreas,, Lundqvist, Magnus,, Lindstrom, Emil, Mardinoglu, Adil, Sivertsson, Asa,, Karlsson, Max J.,, Ayoglu, Burcu,, Uhlen, Mathias, Sivertsson, Asa, Volk, Anna-Luisa,, Nielsen, Jens,, Sjostedt, Evelina, Mahdessian, Diana,, Kotol, David, Katona, Borbala, Kanje, Sara,, Edfors, Fredrik, Zwahlen, Martin, Thul, Peter,, Voldborg, Bjorn G., Nielsen, Jens B,, Mulder, Jan, Haussler, Ragna S., Strandberg, Linnea,, Karlsson, Max J., Schwenk, Jochen M., Nilsson, Peter,, Berling, Anna, Hober, Sophia, Nielsen, Jens B, Malm, Magdalena,, Dannemeyer, Melanie,, Haussler, Ragna S.,, Dannemeyer, Melanie, Mardinoglu, Adil,, Vuu, Jimmy,, Tegel, Hanna, Hober, Sophia,, Uhlen, Mathias,, Dodig-Crnkovic, Tea, Zhong, Wen, Manberg, Anna, Scheffel, Julia, Hong, Mun-Gwan, Nilsson, Peter, Oksvold, Per, Ekblad, Siri,, Voldborg, Bjorn G.,, Oksvold, Per,, Zhong, Wen,, Berling, Anna,, Sjostedt, Evelina,, Manberg, Anna,, von Feilitzen, Kalle, Edfors, Fredrik,, Ayoglu, Burcu, Lundberg, Emma, Thul, Peter, Dodig-Crnkovic, Tea,, Pontén, Fredrik,, Ponten, Fredrik, von Feilitzen, Kalle,, Gummesson, Anders,, Svensson, Anne-Sophie, Sullivan, Devin,, Danielsson, Frida,, Lundqvist, Magnus, Pin, Elisa,, Forsstrom, Bjorn, Ekblad, Siri, Rockberg, Johan,, Lindström, Emil,, Danielsson, Frida, Lindskog, Cecilia,, Robinson, Jonathan, Malm, Magdalena, Pin, Elisa, Mulder, Jan,, Gummesson, Anders, Strandberg, Linnea, Zwahlen, Martin,, Robinson, Jonathan,, Stadler, Charlotte,, Vuu, Jimmy, Volk, Anna-Luisa, Svensson, Anne-Sophie,, Kotol, David,, Scheffel, Julia,, Lundberg, Emma,, Mahdessian, Diana, Rockberg, Johan, Tebani, Abdellah, Katona, Borbala,, Sullivan, Devin, Lindskog, Cecilia, Schwenk, Jochen M.,, Stadler, Charlotte, Bergstrom, Goran, Hong, Mun-Gwan,, Forsstrom, Bjorn,, Tebani, Abdellah,, Fagerberg, Linn,, Sjostedt, E., Mulder, J., Svensson, A-S, Lundberg, E., Hober, S., Tebani, A, Strandberg, L., Hong, M. G., Lindstrom, E., Manberg, A., Danielsson, F., Hober, A., Volk, A. L., Ekblad, S., Oksvold, P., Scheffel, J, Forsstrom, B., Hober, A,, Schwenk, J. M., Nielsen, J., Zwahlen, M., Svensson, A. S., Strandberg, L, Stadler, C., Zhong, W., Tebani, A., Lundqvist, M., Haussler, R. S., Scheffel, J., Lindskog, C., Sullivan, D., Karlsson, MJ, Mahdessian, D., Sivertsson, A., Mardinoglu, A., Ponten, F., Vuu, J., Zhong, W, Robinson, J., Edfors, F, Karlsson, M. J., Edfors, F., Uhlen, M., Dodig-Crnkovic, T., Berling, A., Pin, E., Rockberg, J., Tegel, H., Ayoglu, B., Fagerberg, L., Uhlen, M, Nilsson, P., von Feilitzen, K., Kotol, D., Thul, P., Kotol, D, Katona, B., Kanje, S., Voldborg, B. G., Dannemeyer, M., Malm, M.   +167 more
core   +1 more source

Blood/plasma secretome and microvesicles

, 2013
A major but hitherto overseen component of the blood/plasma secretome is that of extracellular vesicles (EVs) which are shed from all blood cell types. These EVs are made up of microvesicles (MVs) and exosomes.
Lange, S., Kosgodage, U., Azam, S., Stratton, D., Inal, J.M., Antwi-Baffour, S.   +5 more
core   +1 more source

Mesenchymal stromal cell-derived exosome-rich fractionated secretome confers a hepatoprotective effect in liver injury

Stem Cell Research & Therapy, 2018
Background Mesenchymal stromal cells (MSCs) are an attractive therapeutic agent in regenerative medicine. Recently, there has been a paradigm shift from differentiation of MSCs to their paracrine effects at the injury site.
Apeksha Damania, Deepika Jaiman, Arun Kumar Teotia, Ashok Kumar   +3 more
doaj   +1 more source

Secretome-based proteomics reveals sulindac-modulated proteins released from colon cancer cells

, 2009
Although experiments in rodents and human population-based studies have demonstrated the efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) such as sulindac in colorectal cancer (CRC) prevention, a detailed knowledge of the underlying mechanism of
Richard Simpson (9487685), RL Moritz (11223852), H Ji (9893819), David Greening (9478589), EA Kapp (11223837)   +4 more
core   +1 more source

The secretome of Staphylococcus aureus strains with opposite within-herd epidemiological behavior affects bovine mononuclear cell response

Veterinary Research, 2023
Staphylococcus aureus modulates the host immune response directly by interacting with the immune cells or indirectly by secreting molecules (secretome).
Susanna Di Mauro, Joel Filipe, Alessia Facchin, Laura Roveri, Maria Filippa Addis, Valentina Monistero, Renata Piccinini, Giulia Sala, Davide Pravettoni, Clarissa Zamboni, Fabrizio Ceciliani, Cristina Lecchi   +11 more
doaj   +1 more source