Results 251 to 260 of about 61,645 (272)

Bioinformatics tools for secretome analysis

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013
Over recent years, analyses of secretomes (complete sets of secreted proteins) have been reported in various organisms, cell types, and pathologies and such studies are quickly gaining popularity. Fungi secrete enzymes can break down potential food sources; plant secreted proteins are primarily parts of the cell wall proteome; and human secreted ...
Dario, Caccia, Matteo, Dugo, Maurizio, Callari, Italia, Bongarzone   +3 more
openaire   +2 more sources

Regulation of the fungal secretome

Current Genetics, 2016
The ability of countless representatives of the Kingdom Fungi to adapt to and proliferate in diverse environments is facilitated by regulation of their secretomes to respond to changes in environmental conditions and to mediate interactions with other organisms.
Sean W, McCotter, Linda C, Horianopoulos, James W, Kronstad   +2 more
openaire   +2 more sources

Blood/plasma secretome and microvesicles

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013
A major but hitherto overseen component of the blood/plasma secretome is that of extracellular vesicles (EVs) which are shed from all blood cell types. These EVs are made up of microvesicles (MVs) and exosomes. MVs, 100nm-1μm in diameter, are released from the cell surface, and are a rich source of non-conventionally secreted proteins lacking a ...
Jameel M, Inal, Uchini, Kosgodage, Sarah, Azam, Dan, Stratton, Samuel, Antwi-Baffour, Sigrun, Lange   +5 more
openaire   +2 more sources

The secretome in cancer progression

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013
The secretome is the collection of all macromolecules secreted by a cell, and is a vital aspect of cell-cell communication in eukaryotes. In cancer, tumour cells often display secretomes with altered composition compared to the normal tissue from which they are derived.
Paltridge, J., Belle, L., Khew-Goodall, Y.   +2 more
openaire   +4 more sources

Secretome profiling with antibody microarrays

Molecular BioSystems, 2011
Following the advances in human genome sequencing, attention has shifted in part toward the elucidation of the encoded biological functions. Since proteins are the driving forces behind very many biological activities, large-scale examinations of their expression variations, their functional roles and regulation have moved to the central stage.
Shakhawan Abdulrahman, Mustafa, Jörg D, Hoheisel, Mohamed Saiel Saeed, Alhamdani   +2 more
openaire   +2 more sources

Sieving through the cancer secretome

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013
Cancer is among the most prevalent and serious health problems worldwide. Therefore, there is an urgent need for novel cancer biomarkers with high sensitivity and specificity for early detection and management of the disease. The cancer secretome, encompassing all the proteins that are secreted by cancer cells, is a promising source of biomarkers as ...
Qifeng, Lin, Hwee Tong, Tan, Hannah Soo Rei, Lim, Maxey C M, Chung   +3 more
openaire   +2 more sources

Secretomes: The fungal strike force

PROTEOMICS, 2013
Microorganisms, although being very diverse because they comprise prokaryotic organisms such as bacteria or eukaryotic organisms such as fungi, all share an essential exodigester function. The consequence is their essential need to have a secretome adapted to their environment.
Vincent, Girard, Cindy, Dieryckx, Claudette, Job, Dominique, Job   +3 more
openaire   +2 more sources

Human epididymal secretome and proteome

Molecular and Cellular Endocrinology, 2006
The proteins that are neosynthesized and secreted in the different regions of the human epididymis were determined by in vitro biosynthesis of epididymal tubules, and the luminal proteins were collected by microperfusion of each tubule. The preparations were analyzed by two-dimensional gel electrophoresis and the proteins were identified by mass ...
Dacheux, Jean-Louis, Belghazi, Maya, Lanson, Y, Dacheux, Françoise   +3 more
openaire   +5 more sources

Secretome of Human Aortic Valves

2013
One of the major challenges in cardiovascular medicine is to identify candidate biomarker proteins. Between different proteomics studies, the secretome is a valuable tool in the search for biomarkers locally released by a studied tissue and remains particularly important while working with vascular tissues, since the secreted proteins would be probably
Fernando, de la Cuesta, Gloria, Alvarez-Llamas, Felix, Gil-Dones, Verónica M, Darde, Enrique, Calvo, Juan Antonio, López, Fernando, Vivanco, María G, Barderas   +7 more
openaire   +2 more sources

Hallmarks of the metabolic secretome

Trends in Endocrinology & Metabolism
The identification of novel secreted factors is advancing at an unprecedented pace. However, there is a critical need to consolidate and integrate this knowledge to provide a framework of their diverse mechanisms, functional significance, and inter-relationships.
Saranya C. Reghupaty, Nicholas R. Dall, Katrin J. Svensson   +2 more
openaire   +2 more sources