Results 181 to 190 of about 326,424 (312)

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Map of the neuronal O-glycoproteome reveals driver functions in the regulated secretory pathway. [PDF]

J Biol Chem
Madsen TD, Topaktas AB, Dworkin LA, Hintze J, Hansen LH, Nikpour M, Lackman JJ, Goth CK, Larson G, Shiplett EJ, Edmondson AC, Zhou Z, Miller RL, Joshi HJ, Vakhrushev SY, Schjoldager KT.   +15 more
europepmc   +1 more source

Endoplasmic reticulum secretory pathway: Potential target against SARS-CoV-2. [PDF]

Virus Res, 2022
Upadhyay M, Gupta S.
europepmc   +1 more source

High-throughput trapping of secretory pathway genes in mouse embryonic stem cells [PDF]

, 2006
Silke De-Zolt
openalex   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Subcellular localization of SARS-CoV-2 E and 3a proteins along the secretory pathway. [PDF]

J Mol Histol
Hinkle JJ, Trychta KA, Wires ES, Osborn RM, Leach JR, Faraz ZF, Svarcbahs R, Richie CT, Dewhurst S, Harvey BK.   +9 more
europepmc   +1 more source

Fluorescence Lifetime Imaging of pH along the Secretory Pathway. [PDF]

ACS Chem Biol, 2022
Linders PTA, Ioannidis M, Ter Beest M, van den Bogaart G.   +3 more
europepmc   +1 more source

LRP1 modulates APP trafficking and APP metabolism within compartments of the secretory pathway. Increased AICD generation is ineffective in nuclear translocation and transcriptional activation

, 2008
Elaine Waldron
openalex   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

The secretory pathway in Tetrahymena is organized for efficient constitutive secretion at ciliary pockets. [PDF]

iScience
Jiang YY, Kumar S, Turkewitz AP.
europepmc   +1 more source