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Compartments of the Early Secretory Pathway
1994The secretory pathway consists of a set of compartments responsible for the assembly and modification of proteins destined for secretion, for transport to the plasma membrane, and to the other organelles of the cell. The classical description of the secretory pathway comprises the endoplasmic reticulum (ER) as the site of protein synthesis and first ...
R J, Hendriks, S D, Fuller
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Novel Secretory Pathways in Plasmodium?
Parasitology Today, 1999The secretion of proteins from intraerythrocytic stages of Plasmodium falciparum into the infected host cell is still poorly understood. A recent proposal that two distinct, mutually exclusive, secretory compartments may exist within the parasite cell has received much attention.
D, Mattei +3 more
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Molecular Sorting in the Secretory Pathway
Science, 1989Proteins can be secreted from animal cells by either a constitutive or a regulated pathway; those destined for regulated secretion are actively sorted into dense-core secretory granules. Although sorting is generally assumed to be accomplished by specific carriers, the nature of these carriers remains elusive.
K N, Chung +3 more
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1994
Abstract This, the latest in the Sambrook and Tooze Guidebook Series enables non-specialists to rapidly gain access to unfamiliar work surrounding the secretory pathways. Detailing both the established and the experimental, this book outlines how recent work has established a role for the secretory pathway in the regulation of gene ...
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Abstract This, the latest in the Sambrook and Tooze Guidebook Series enables non-specialists to rapidly gain access to unfamiliar work surrounding the secretory pathways. Detailing both the established and the experimental, this book outlines how recent work has established a role for the secretory pathway in the regulation of gene ...
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Uncoupling of the secretory pathways for IgA and secretory component by cholestasis
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1987Circulating polymeric immunoglobulin A (IgA) binds to secretory component (SC) on the surface of rat hepatocytes and is internalized and transported by vesicles to the canalicular membrane where the IgA-SC complex is secreted into bile. To further characterize this transport pathway, we examined the effects of bile flow reduction or transient bile ...
T M, Kloppel +3 more
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Entering the secretory pathway
1994Abstract In prokaryotic and eukaryotic cells, specialized processes such as secretion and signal transduction, as well as the enzymatic reactions of intermediary metabolism, are organized into membranes and membrane-enclosed compartments.
Jonathan Rothblatt +2 more
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The secretory pathway in yeast
Trends in Biochemical Sciences, 1982Abstract Yeast mutants that are temperature-sensitive for secretion and growth accumulate secretory organelles which contain glycoprotein intermediates. The secretory pathway, defined by these mutants, is also responsible for plasma membrane and vacuole assembly.
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