Advanced Healthcare Materials, EarlyView.This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim +6 more
wiley +1 more source
The Saccharomyces cerevisiae SEC14 Gene Encodes a Cytosolic Factor That Is Required for Transport of Secretory Proteins from the Yeast Golgi Complex [PDF]
, 1989 We have obtained and characterized a genomic clone of SEC14, a Saccharomyces cerevisiae gene whose product is required for export of yeast secretory proteins from the Golgi complex.
Bankaitis, Vytas A. +3 more
core +1 more source
Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies
Advanced Healthcare Materials, EarlyView.Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer +10 more
wiley +1 more source
Pulse of inflammatory proteins in the pregnant uterus of European polecats (Mustela putorius) leading to the time of implantation [PDF]
, 2017 Uterine secretory proteins protect the uterus and conceptuses against infection, facilitate implantation, control cellular damage resulting from implantation, and supply pre-implantation embryos with nutrients.
Burchmore, Richard J.S. +2 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun +11 more
wiley +1 more source
Changes in expression and activity of the secretory pathway Ca2+ATPase 1 (SPCA1) in A7r5 vascular smooth muscle cells cultured at different glucose concentrations [PDF]
, 2009 Diabetes mellitus-related vascular disease is often associated with both a dysregulation of Ca\(^{2+}\) homoeostasis and enhanced secretory activity in VSMCs (vascular smooth muscle cells).
Al-Bader +34 more
core +6 more sources
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Brazilian Journal of BiologyThe present study aims at providing a detailed description of the histology, as well as the first histochemical characterization, of the secretory cells of the epidermis, pharynx, and copulatory organs of Choeradoplana iheringi, in order to give further ...
S. A. de Souza, A. M. Leal-Zanchet
doaj +1 more source
Anatomy and Histology of the Male Reproductive Complex of the Onion Maggot Fly, \u3ci\u3eDelia Antiqua\u3c/i\u3e, (Diptera: Anthomyiidae) Including Some Comparisons With \u3ci\u3eD. Platura\u3c/i\u3e and \u3ci\u3eD. Radicum\u3c/i\u3e [PDF]
, 2018 In Delia antiqua (Meigen) (Diptera: Anthomyiidae), the male reproductive complex is composed of a pair of testes, paired vas deferens connecting the testes to the anterior ejaculatory duct, and a pair of paragonial (accessory) glands. Each D.
Grimnes, Karin A, Miller, James R
core +2 more sources
Serum relaxin and the major endometrial secretory proteins in in-vitro fertilization and down-regulated hormone-supported and natural cycle frozen embryo transfer [PDF]
, 1996 Ian Arthur +3 more
openalex +1 more source