Results 61 to 70 of about 28,093 (313)
Biomechanics of transverse axis of medial longitudinal arch of children's foot based on 3D scanning
Frontiers in Pediatrics, 2023 ObjectiveTo explore the application value of 3D scanning to obtain the parameters of transverse axis of medial longitudinal arch of foot in the biomechanical evaluation of transverse axis of medial longitudinal arch of foot in children.MethodThe feet of ...
Qinglin Liu +6 more
doaj +1 more source
Riemannian Manifolds with Positive Sectional Curvature [PDF]
, 2014 This is a survey of recent results on manifolds with positive curvature from a series of lecture given in Guanajuato, Mexico in 2010. It also contains some hitsorical comments.
openaire +2 more sources
On the Sectional Curvature Along Central Configurations [PDF]
Regular and Chaotic Dynamics, 2018 14 pages, 4 ...
Jackman, Connor, Meléndez, Josué
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Nasal and temporal curvatures of lamina CRIBROSA in myopic eyes
Scientific Reports, 2022 Little is known about the myopic characteristics of lamina cribrosa (LC) curvature. As such, we investigated nasal and temporal LC curvatures in myopia.
Sooyeon Choe +6 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Developments around positive sectional curvature [PDF]
Surveys in Differential Geometry, 2008 This is not in any way meant to be a complete survey on positive curvature. Rather it is a short essay on the fascinating changes in the landscape surrounding positive curvature. In particular, details and many results and references are not included, and things are not presented in chronological order.
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source