Results 31 to 40 of about 19,845 (223)

Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex [PDF]

, 2012
The bacterial ATPase SecA and protein channel complex SecYEG form the core of an essential protein translocation machinery. The nature of the conformational changes induced by each stage of the hydrolytic cycle of ATP and how they are coupled to protein ...
Alice Robson, Bauer, Berger, Bessonneau, Breyton, Brundage, Cannon, Dalal, Deville, Ding, Duong, Egea, Erlandson, Erlandson, Gelis, Gold, Gold, Gold, Hizlan, Hunt, Ian Collinson, Karamanou, Lill, Or, Osborne, Osborne, Park, Park, Piggot, Piggot, Richard B. Sessions, Robson, Robson, Robson, Sarah Whitehouse, Tam, Van den Berg, Vicki A.M. Gold, William J. Allen, Wolf, Woodbury, Zimmer, Zimmer   +42 more
core   +2 more sources

Characterization of the UGA-recoding and SECIS-binding activities of SECIS-binding protein 2 [PDF]

RNA Biology, 2014
Selenium, a micronutrient, is primarily incorporated into human physiology as selenocysteine (Sec). The 25 Sec-containing proteins in humans are known as selenoproteins. Their synthesis depends on the translational recoding of the UGA stop codon to allow Sec insertion.
Bubenik, Jodi L, Miniard, Angela C, Driscoll, Donna M   +2 more
openaire   +2 more sources

HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon

eLife, 2019
The bacterial Sec translocon is a multi-protein complex responsible for translocating diverse proteins across the plasma membrane. For post-translational protein translocation, the Sec-channel – SecYEG – associates with the motor protein SecA to mediate ...
Zainab Ahdash, Euan Pyle, William John Allen, Robin A Corey, Ian Collinson, Argyris Politis   +5 more
doaj   +1 more source

Development and Validation of a New TaqMan Real-Time PCR for Detection of ‘Candidatus Phytoplasma pruni’

Pathogens, 2020
Phytoplasmas of the 16SrIII group are wide spread, and have a broad plant host range. Among these, ‘Candidatus phytoplasma pruni’ (‘Ca. P. pruni’; phytoplasmas of 16SrIII subgroup A) can cause serious diseases in Prunus species and ‘Ca. P. pruni’-related
Zala Kogej, Marina Dermastia, Nataša Mehle   +2 more
doaj   +1 more source

Molecular Characterization of Leptospira Species Detected in the Kidneys of Slaughtered Livestock in Abattoirs in Gauteng Province, South Africa

Pathogens, 2023
Leptospira was investigated in kidneys (n = 305) from slaughtered livestock in the Gauteng Province abattoirs, South Africa, using a culture medium to isolate Leptospira, followed by the LipL32 qPCR to detect Leptospira DNA.
Banenat B. Dogonyaro, Henriette van Heerden, Andrew D. Potts, Folorunso O. Fasina, Arnau Casanovas-Massana, Francis B. Kolo, Christine Lötter, Charles Byaruhanga, Albert I. Ko, Elsio A. Wunder, Abiodun A. Adesiyun   +10 more
doaj   +1 more source

Design of an adaptive neural predictive nonlinear controller for nonholonomic mobile robot system based on posture identifier in the presence of disturbance [PDF]

, 2020
This paper proposes an adaptive neural predictive nonlinear controller to guide a nonholonomic wheeled mobile robot during continuous and non-continuous gradients trajectory tracking.
Abbod, MF, Al-Araji, AS, Al-Raweshidy, HS   +2 more
core   +1 more source

Diagnostic accuracy of genetic markers and nucleic acid techniques for the detection of Leptospira in clinical samples: A meta-analysis.

PLoS Neglected Tropical Diseases, 2020
BACKGROUND:Leptospirosis is often difficult to diagnose because of its nonspecific symptoms. The drawbacks of direct isolation and serological tests have led to the increased development of nucleic acid-based assays, which are more rapid and accurate.
Jia-Yong Lam, Gary Kim-Kuan Low, Hui-Yee Chee   +2 more
doaj   +1 more source

Comparison of DNA extraction methods for molecular identification of pathogenic Leptospira in the urine samples

Health Science Journal of Indonesia, 2020
Latar belakang: Leptospirosis merupakan zoonosis penting di dunia, yang masih sering terjadi salah diagnosis. Deteksi laboratorium Leptospira menjadi tantangan karena bakterimea cukup singkat untuk dideteksi molekuler, namun antibodi juga muncul sangat ...
Farida Dwi Handayani, Rahmi Ayu Wijayaningsih, Muhammad Hussein Gasem, Tri Wibawa   +3 more
doaj   +1 more source

Serovar diversity of pathogenic Leptospira circulating in the French West Indies. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: Leptospirosis is one of the most important neglected tropical bacterial diseases in Latin America and the Caribbean. However, very little is known about the circulating etiological agents of leptospirosis in this region.
Pascale Bourhy, Cécile Herrmann Storck, Rafaelle Theodose, Claude Olive, Muriel Nicolas, Patrick Hochedez, Isabelle Lamaury, Farida Zinini, Sylvie Brémont, Annie Landier, Sylvie Cassadou, Jacques Rosine, Mathieu Picardeau   +12 more
doaj   +1 more source

Electrostatics inside the SecY Translocon [PDF]

Biophysical Journal, 2015
SecY constitutes the core of the highly conserved SecYEG translocon complex that governs the translocation or integration of proteins across or into cytoplasmic membranes. Besides its role of guiding nascent membrane protein chains into the lipid bilayer, it also plays an important role in determining transmembrane topology via the so-called positive ...
Capponi, Sara, White, Stephen H
openaire   +2 more sources