Results 11 to 20 of about 19,845 (223)

Host-Driven Genetic Diversity of <i>Leptospira</i> in the Americas: A Continental Perspective. [PDF]

open access: yesTransbound Emerg Dis
Leptospira is a genetically diverse genus of spirochetes comprising over 68 species, including several pathogenic taxa such as L. interrogans, L. santarosai, L. noguchii, and L. weilii. These bacteria infect a wide range of vertebrates, especially mammals, with infected animals serving as renal carriers that excrete the pathogen through urine.
Suárez-Galaz A   +13 more
europepmc   +2 more sources

A unified evolutionary origin for the ubiquitous protein transporters SecY and YidC

open access: yesBMC Biology, 2021
Background Protein transporters translocate hydrophilic segments of polypeptide across hydrophobic cell membranes. Two protein transporters are ubiquitous and date back to the last universal common ancestor: SecY and YidC.
Aaron J. O. Lewis, Ramanujan S. Hegde
doaj   +1 more source

SecY-SecA fusion protein retains the ability to mediate protein transport. [PDF]

open access: yesPLoS ONE, 2017
In bacteria, the membrane protein complex SecY/E/G and SecA ATPase are essential for protein translocation. About 30% of newly synthesized proteins in the cytosol are targeted to and translocated across the cytoplasmic membrane by the Sec factors ...
Yasunori Sugano   +4 more
doaj   +1 more source

Unlocking the Bacterial SecY Translocon [PDF]

open access: yesStructure, 2016
The Sec translocon performs protein secretion and membrane protein insertion at the plasma membrane of bacteria and archaea (SecYEG/β), and the endoplasmic reticular membrane of eukaryotes (Sec61). Despite numerous structures of the complex, the mechanism underlying translocation of pre-proteins, driven by the ATPase SecA in bacteria, remains ...
Corey, Robin A   +6 more
openaire   +4 more sources

Molecular identification of ‘Candidatus Phytoplasma solani’ using SecY and Vmp1 Genes in Tomato Plants from Van province

open access: yesYüzüncü Yıl Üniversitesi Tarim Bilimleri Dergisi, 2021
Tomato (Solanum lycopersicum) is one of the most financially important vegetable crops. It is a species belonging to the Solanaceae family and is cultivated in many countries, including Turkey. The natural presence of ‘Candidatus Phytoplasma solani’ (‘Ca.
Mustafa USTA   +2 more
doaj   +1 more source

Tapered optical fiber DNA biosensor for detecting Leptospira DNA

open access: yesAsian Pacific Journal of Tropical Medicine, 2023
Objective: To establish a DNA detection platform based on a tapered optical fiber to detect Leptospira DNA by targeting the leptospiral secY gene. Methods: The biosensor works on the principle of light propagating in the special geometry of the optical ...
Jia-Yong Lam   +2 more
doaj   +1 more source

Dynamic Organization of SecA and SecY Secretion Complexes in the B. subtilis Membrane.

open access: yesPLoS ONE, 2016
In prokaryotes, about one third of cellular proteins are translocated across the plasma membrane or inserted into it by concerted action of the cytoplasmic ATPase SecA and the universally conserved SecYEG heterotrimeric polypeptide-translocating pore ...
Alex Dajkovic   +3 more
doaj   +1 more source

Membrane Insertion of the M13 Minor Coat Protein G3p Is Dependent on YidC and the SecAYEG Translocase

open access: yesViruses, 2021
The minor coat protein G3p of bacteriophage M13 is the key component for the host interaction of this virus and binds to Escherichia coli at the tip of the F pili.
Farina Kleinbeck, Andreas Kuhn
doaj   +1 more source

Bacterial protein translocation requires only one copy of the SecY complex in vivo [PDF]

open access: yes, 2012
The transport of proteins across the plasma membrane in bacteria requires a channel formed from the SecY complex, which cooperates with either a translating ribosome in cotranslational translocation or the SecA ATPase in post-translational translocation.
Park, Eunyong, Rapoport, Tom A.
core   +1 more source

Bioinformatics describes novel Loci for high resolution discrimination of leptospira isolates. [PDF]

open access: yesPLoS ONE, 2010
Leptospirosis is one of the most widespread zoonoses in the world and with over 260 pathogenic serovars there is an urgent need for a molecular system of classification. The development of multilocus sequence typing (MLST) schemes for Leptospira spp.
Gustavo M Cerqueira   +6 more
doaj   +1 more source

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