Results 61 to 70 of about 21,101 (237)

Survey and multigene characterization of stolbur phytoplasmas on various plant species in Serbia

Phytopathologia Mediterranea, 2013
Stolbur phytoplasmas were detected in 116 out of more than 200 samples from nine plant species col- lected in 2009‒2010 in Serbia. Phytoplasmas were detected and identified by restriction fragment length polymor- phism (RFLP) analysis of polymerase chain
Jelena MITROVIĆ, Snežana PAVLOVIĆ, Bojan DUDUK   +2 more
doaj   +1 more source

Novel Antimicrobials from Uncultured Bacteria Acting against Mycobacterium tuberculosis

mBio, 2020
Mycobacterium tuberculosis, which causes tuberculosis (TB), is estimated to infect one-third of the world’s population. The overall burden and the emergence of drug-resistant strains of Mycobacterium tuberculosis underscore the need for new therapeutic ...
Jeffrey Quigley, Aaron Peoples, Asel Sarybaeva, Dallas Hughes, Meghan Ghiglieri, Catherine Achorn, Alysha Desrosiers, Cintia Felix, Libang Liang, Stephanie Malveira, William Millett, Anthony Nitti, Baldwin Tran, Ashley Zullo, Clemens Anklin, Amy Spoering, Losee Lucy Ling, Kim Lewis   +17 more
doaj   +1 more source

Export of honeybee prepromelittin in Escherichia coli depends on the membrane potential but does not depend on proteins secA and secY [PDF]

, 1989
Honeybee prepromelittin (70 amino acid residues), the precursor of an eukaryotic secretory protein, and a hybrid protein between prepromelittin and mouse dihydrofolate reductase (257 amino acid residues) were expressed in Escherichia coli and ...
Cobet, Werner W. E., Mollay, Christa, Müller, Günter, Zimmermann, Richard   +3 more
core  

Impaired transport of intrinsically disordered proteins through the Sec61 and SecY translocon; implications for prion diseases

Prion, 2018
The prion protein (PrP) is composed of two major domains of similar size. The structured C-terminal domain contains three alpha-helical regions and a short two-stranded beta-sheet, while the N-terminal domain is intrinsically disordered.
Sebastian Jung, J. Tatzelt
semanticscholar   +1 more source

Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY [PDF]

, 2005
During their biosynthesis, many proteins pass through the membrane via a hydrophilic channel formed by the heterotrimeric Sec61/SecY complex. Whether this channel forms at the interface of multiple copies of Sec61/SecY or is intrinsic to a monomeric ...
Cannon, Kurt S., Clemons, William M., Jr., Or, Eran, Rapoport, Tom A., Shibata, Yoko   +4 more
core  

Comparative analysis of current diagnostic PCR assays in detecting pathogenic Leptospira isolates from environmental samples

Asian Pacific Journal of Tropical Medicine, 2019
Objective: To compare the efficiency of routine diagnostic PCR assays in detecting pathogenic Leptospira isolated from water and soils. Methods: Seven routine assays targeting six genes (lipL32, flaB, gyrB, lfb1, secY and ligB) were evaluated and ...
May-Ling Yap, Zamberi Sekawi, Hui-Yee Chee, Han Kiat Alan Ong, Vasantha Kumari Neela   +4 more
doaj   +1 more source

Profiling an Enhanced IL‐6 Expression Distinguishes Host Susceptibility to Primary and Secondary Infections of the Dengue Virus in an Ex Vivo Whole‐Blood Coculture Model

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Dengue virus (DENV) infection can potentially lead to severe dengue disease due to the risk of antibody‐dependent enhancement. This study reports a comparative analysis of the host cytokine/chemokine response triggered by primary and secondary DENV infections using an artificial ex vivo whole‐blood coculture model to simulate viremia during the acute ...
Josephine Diony Nanda, Ming-Kai Jhan, Rahmat Dani Satria, Yung-Ting Wang, Tzong-Shiann Ho, Herdiantri Sufriyana, Emily Chia-Yu Su, Chiou-Feng Lin, Biswadeep Das   +8 more
wiley   +1 more source

Membrane protein insertion and assembly by the bacterial holo-translocon SecYEG-SecDF-YajC-YidC [PDF]

, 2016
Protein secretion and membrane insertion occur through the ubiquitous Sec machinery. In this system, insertion involves the targeting of translating ribosomes via the signal recognition particle and its cognate receptor to the SecY (bacteria and archaea)/
Alvira-de-Celis, Sara, Berger, Imre, Collinson, Ian, Dafforn, Timothy, Deckers-Hebestreit, Gabriele, Komar, Joanna, Lee, S, Martin, Remy, Nijeholtb, Jelger A. Lycklama A., Schaffitzel, Christiane, Schulze, Ryan   +10 more
core   +4 more sources

The protein-conducting channel SecYEG [PDF]

, 2004
In bacteria, the translocase mediates the translocation of proteins into or across the cytosolic membrane. It consists of a membrane embedded protein-conducting channel and a peripherally associated motor domain, the ATPase SecA. The channel is formed by
Driessen, AM, van der Does, C, Veenendaal, AKJ, Veenendaal, Andreas K.J.   +3 more
core   +2 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, Volume 599, Issue 24, Page 3569-3590, December 2025.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source