Results 61 to 70 of about 1,154,828 (344)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Discharge and turbidity of the regulated River Tees. Variance spectrum analysis [PDF]

, 1985
High suspended sediment loads may be deleterious to adult salmonids and invertebrates in gravel-bedded streams. Further, the accumulation of fine material in the interstices of the gravel may have an adverse impact on the recruitment of the young stages ...
Carling, P.A., Douglas, N.H.N.
core  

Extreme flood-driven fluvial bank erosion and sediment loads: direct process measurements using integrated Mobile Laser Scanning (MLS) and hydro-acoustic techniques: Direct measurement of flood-driven erosion using MLS and MBES [PDF]

, 2016
Copyright © 2016 John Wiley & Sons, Ltd. This methods paper details the first attempt at monitoring bank erosion, flow and suspended sediment at a site during flooding on the Mekong River induced by the passage of tropical cyclones.
Aalto, Rolf, Best, James L., Darby, Stephen E., Hackney, Christopher R., Lague, Dimitri, Leyland, Julian, Nicholas, Andrew P., Parsons, Daniel R.   +7 more
core   +3 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Relationship between Precipitation Just above the Lava Dome and Displacement of the Dome Using X-Band MP Radar at Unzen Fugendake

Proceedings, 2023
Since its last eruption in 1990–1995, the Unzen volcano (Shimabara Peninsula, Japan) has been quiescent. At its summit, a complex dacitic dome spreads toward the East, in the direction of the Mizunashigawa valley.
Rikuto Daikai, Christopher Gomez, Balazs Bradak, Norifumi Hotta, Yoshinori Shinohara   +4 more
doaj   +1 more source

Lateral Marsh Edge Erosion as a Source of Sediments for Vertical Marsh Accretion [PDF]

, 2018
With sea level rise accelerating and sediment inputs to the coast declining worldwide, there is concern that tidal wetlands will drown. To better understand this concern, sources of sediment contributing to marsh elevation gain were computed for Plum ...
Barbier, Bauer, Blum, Blum, Cahoon, Cavatorta, Claessens, Cook, Costanza, Day, Day, Dhillon, Donnelly, Donnelly, Engelhart, Eyre, Fagherazzi, Fagherazzi, Foley, Forbrich, French, Ganju, Ganju, Geyer, Gittman, Gosselink, Hayden, Hein, Hobbs, Hopkinson, Hughes, Kirwan, Kirwan, Kirwan, Koch, Lane, Leonardi, Leonardi, Leonardi, Levin, Magirl, Marcus, Mariotti, Mariotti, Mariotti, Mattheus, McGeehin, McKee, Meade, Meade, Megonigal, Millette, Milliman, Mineau, Morris, Morris, Morris, Morris, Morris, Mudd, Pasternack, Pavich, Priestas, Rahmstorf, Raymond, Redfield, Redfield, Redfield, Reed, Rovere, Schmidt, Schwimmer, Sholkovitz, Stuiver, Swales, Syvitski, Townsend, Trimble, Vallino, Vallino, Walsh, Warrick, Warrick, Watson, Weston, Wilson, Wollheim, Wollheim, Worm, Yarbro, Zhao   +90 more
core   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Water ecological health evaluation of urban river: a case study of Zaogang River, China

Frontiers in Ecology and Evolution
The ecological health of urban rivers serves as a critical indicator of the overall health of urban ecosystems. The water ecological health status of the Zaogang River in Changzhou City was evaluated; nine sections of the river and the Old Zaogang River ...
Jiaqi Zhang, Jiaqi Xiang, Qiwen Ma, Chunhui Li, Xiangen Xu   +4 more
doaj   +1 more source