Results 91 to 100 of about 321,831 (296)

On extracting sediment transport information from measurements of luminescence in river sediment [PDF]

, 2016
Accurately quantifying sediment transport rates in rivers remains an important goal for geomorphologists, hydraulic engineers, and environmental scientists.
Gray, H.J., Mahan, S.A., McGuire, C., Rhodes, E.J., Tucker, G.E.   +4 more
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Challenges in transferring knowledge between scales in coastal sediment dynamics

Frontiers in Marine Science, 2015
‘Packaging’ coastal sediment transport into discrete temporal and spatial scale bands is necessary for measurement programs, modelling, and design. However, determining how to best measure and parameterize information, to transfer between scales, is not ...
Shari L Gallop, Shari L Gallop, Michael eCollins, Michael eCollins, Charitha Bandula Pattiaratchi, Matthew John Eliot, Cyprien eBosserelle, Marco eGhisalberti, Lindsay Boyd Collins, Ian eEliot, Paul L.A. Erftemeijer, Piers eLarcombe, Piers eLarcombe, Ionan eMarigomez, Tanya eStul, David John White   +15 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Mean and fluctuating suspended sediment concentration measurements using ADV [PDF]

, 2012
The present experimental research looks for ways to improve fine sediment transport measurements with ADV by further investigating the factors influencing the backscatter intensity of the acoustic wave.
De Mulder, Tom, Decrop, Boudewijn, Toorman, Erik   +2 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The snowmelt period in a Mediterranean High Mountain Catchment : runoff and sediment transport

Cuadernos de Investigación Geográfica, 2013
Runoff and sediment transport during the snowmelt period (May June, 2004) in the Izas catchment (Central Pyrenees) were studied to obtain a sediment balance and to assess the relative importance of sediment transport during that period.
N. Lana-Renault, B. Alvera, J. M. García Ruiz   +2 more
doaj   +1 more source