Results 71 to 80 of about 201,517 (307)
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Modelling soil erosion and transport in the Burrishoole catchment, Newport, Co. Mayo, Ireland [PDF]
, 2005 The Burrishoole catchment is situated in County Mayo, on the northwest coast of the Republic of Ireland. Much of the catchment is covered by blanket peat that, in many areas, has become heavily eroded in recent years. This is thought to be due, primarily,
Dillane, Mary +5 more
core
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Water and sediment yields from two catchments with different land cover areas
Journal of Degraded and Mining Lands Management, 2017 Land cover and human activities affect water yield and soil erosion-sedimentation in a catchment. Therefore, a study to obtain information of water and sediment yields from two catchments covered by different land cover areas has been conducted in ...
Tyas Mutiara Basuki
doaj +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
International Journal of Technology, 2015 The sediment yield is defined as the amount of sediment discharged by an area for a given period of time. Schaffernak proposed to estimate sediment yield in a watershed based on a sediment duration curve.
Dwita Sutjiningsih +2 more
doaj +1 more source
Hydrological Alteration Index as an Indicator of the Calibration Complexity of Water Quantity and Quality Modeling in the Context of Global Change [PDF]
, 2019 Modeling is a useful way to understand human and climate change impacts on the water resources of agricultural watersheds. Calibration and validation methodologies are crucial in forecasting assessments.
Bodoque, José María +12 more
core +6 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A circumpolar perspective on fluvial sediment flux to the Arctic ocean [PDF]
, 2002 Quantification of sediment fluxes from rivers is fundamental to understanding land‐ocean linkages in the Arctic. Numerous publications have focused on this subject over the past century, yet assessments of temporal trends are scarce and consensus on ...
Holmes, Robert M. +2 more
core +2 more sources