Results 81 to 90 of about 34,260 (258)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Research on Impacts of Different Slope Gradientson Runoff and Sediment Yield in Dabie Mountains

open access: yesRenmin Zhujiang, 2020
Dabie Mountains is a national key prevention and protection area for water and soilloss. Aiming at the problem of soil and water loss in Dabie Mountains, and taking the field flowplot of the soil and water conservation test station in Huoshan County as ...
YIN Jinfan   +6 more
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Estimating long term sediment yields from sediment core analysis

open access: yesAnnals of Warsaw University of Life Sciences - SGGW. Land Reclamation, 2010
Estimating long term sediment yields from sediment core analysis Sediment cores from lakes and reservoirs can be used to estimate sediment yields. In proglacial lakes, the bed sediment typically accumulates as varves, reflecting changes in seasonal and annual sedimentation.
Patricia Kennie, Jim Bogen, Hans Olsen
openaire   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The effects of geomorphic controls on sediment yield in the andean rivers of Colombia

open access: yesLatin American Journal of Sedimentology and Basin Analysis, 2021
This paper examines sediment yield rates and its response to control variables in the principal rivers of Colombian draining into the Caribbean and Pacific coasts.
Juan D. Restrepo   +2 more
doaj   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Application of GeoWEPP for Determining Sediment Yield and Runoff in the Orcan Creek Watershed in Kahramanmaras, Turkey

open access: yesSensors, 2008
The geo-spatial interface of the WEPP model called GeoWEPP uses digital geo-referenced information integrated with the most common GIS tools to predict sedimentyield and runoff.
Muzaffer Cetiner   +4 more
doaj  

Spatio-Temporal Dynamics of Sediment yield across the Imo River Basin South- East Nigeria

open access: yesInternational Journal of Environment and Geoinformatics, 2020
Soil and water are the two main natural resources that sustain human existence on earth. Proper monitoring and maintenance of these resources are done on the basin level. The IRB drains an area of 7,951.03 km2.
Amara Ethel Uzor-Totty   +1 more
doaj   +1 more source

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