Results 91 to 100 of about 649,092 (336)

Type I X-ray Bursts at Low Accretion Rates [PDF]

, 2006
Neutron stars, with their strong surface gravity, have interestingly short timescales for the sedimentation of heavy elements. Recent observations of unstable thermonuclear burning (observed as X-ray bursts) on the surfaces of slowly accreting neutron ...
Brown, Edward F., Peng, Fang, Truran, James W.   +2 more
core   +4 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Assessing Differences in Groundwater Hydrology Dynamics Between In Situ Measurements and GRACE-Derived Estimates via Machine Learning: A Test Case of Consequences for Agroecological Relationships Within the Yazoo–Mississippi Delta (USA)

Hydrology
In situ groundwater monitoring is critical for irrigated agroecosystems and informs land cover changes. Yet, such data can pose management challenges and confound agroecological relationships.
Lucas J. Heintzman, Zahra Ghaffari, Abdel R. Awawdeh, Damien E. Barrett, Lance D. Yarbrough, Greg Easson, Matthew T. Moore, Martin A. Locke, Hakan I. Yasarer   +8 more
doaj   +1 more source

Soil of the lower valley of the Dragonja river (Slovenia)

Acta Agriculturae Slovenica, 2015
Soil of the lower valley of the river Dragonja developed under specific soil-forming factors. Soil development in the area was influenced by alluvial sediments originating from surrounding hills, mostly of flysch sequence rocks, as a parent material, Sub-
Tomaž PRUS, Nina ZUPANČIČ, Helena GRČMAN   +2 more
doaj   +1 more source

The effect of optimism bias and governmental action on siltation management within Japanese reservoirs surveyed via artificial neural network

Big Earth Data, 2020
Reservoirs are installed as long-term assets to guarantee water and energy security for decades, if not centuries. However, the effect of siltation undermines reservoirs’ sustainability because it significantly reduces the reservoirs’ original capacity ...
Tobias Landwehr, Sameh Ahmed Kantoush, Claudia Pahl-Wostl, Tetsuya Sumi, Mitsuteru Irie   +4 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Sedimentary processes in the Thau Lagoon (France): From seasonal to century time scales [PDF]

, 2007
As a part of the MICROBENT programme, an investigation of the sedimentation framework was carried out at the water-sediment interface in the Thau Lagoon (French Mediterranean coast). Two main sites, C4 in the middle of the lagoon and C5 near oyster farms,
Gilbert, Franck, Jouanneau, Jean-Marie, Jézéquel, Didier, Lecroart, Pascal, Radakovitch, Olivier, Schmidt, Sabine, Weber, Olivier   +6 more
core   +4 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The Analysis of Sustainable Development Dam in Way Sekampung, Lampung

Jurnal Teknik Hidraulik, 2018
The availability of water resources provides many benefits for the welfare of all human being. The Decrease of the availability of water resources is caused by various reasons, including as environmental damage of catchment area, human activities, land ...
Mirza Nirwansyah, Cecep Kusmana, Eriyatno Eriyatno, M.Yanuar J. Purwanto   +3 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source