Results 101 to 110 of about 606,049 (285)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Coral communities and reefs of Ballena Marine National Park, Pacific coast of Costa Rica

open access: yesCiencias Marinas, 2005
The coral communities and reefs at Ballena Marine National Park, on the southern Pacific coast of Costa Rica, were studied using three 10-m long transects per site, parallel to the coast, with 1-m2 quadrants.
Juan José Alvarado   +3 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Données nouvelles sur la dynamique fluviale postglaciaire et la sédimentation des fonds de vallée en Bretagne. Le cas de la vallée du Steïr près de Quimper (Finistère, France)

open access: yesPhysio-Géo, 2018
The building of the road to bypass of the town of Quimper (Finistère, Brittany) has allowed the discovery of a La Tene human settlement in the floodplain of the Steïr river valley upstream of Quimper at Kergolvez.
Alain Hénaff, Elven Le Goff
doaj   +1 more source

South Atlantic continental margins of Africa: a comparison of the tectonic vs climate interplay on the evolution of equatorial west Africa and SW Africa margins

open access: yes, 2005
The comparative review of 2 representative segments of Africa continental margin: the equatorial western Africa and the SW Africa margins, helps in analysing the main controlling factors on their development.
Anka, Zahie, Seranne, Michel
core   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Endoparasites Determined by Fecal Examination in Sheep in Erzurum Province

open access: yesTürkiye Parazitoloji Dergisi, 2019
Objective:The aim of the current study was to determine the presence and prevalence of Eimeria and helminth species in sheep raised in Erzurum province by using fecal examination.Methods:Faecal samples were collected from a total of 784 sheep raised in ...
Muzaffer Akyüz   +4 more
doaj   +1 more source

Coastal sedimentation [PDF]

open access: yes
Several important coastal sedimentation problems are identified. Application of existing or anticipated remote sensing techniques to examine these problems is considered.
Schubel, J. R.
core   +1 more source

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