Results 101 to 110 of about 649,092 (336)

Controls on channel morphodynamics in the Yellow River Estuary: Insights from a multi-method assessment under an evolving multi-channel regime

International Journal of Sediment Research
The Yellow River Estuary (YRE) in China has transitioned to a complex multi-channel regime since 2013, making understanding terminal channel morphodynamics crucial for effective water and sediment management.
Yanjie Sun, Xiaolong Song, Haijue Xu, Yuchuan Bai   +3 more
doaj   +1 more source

THE FEATURES OF THE GEOLOGICAL STRUCTURE AND SEDIMENTATION OF THE EARLY CRETACEOUS SITE OF THE TERRESTRIAL VERTEBRATES OF SHESTAKOVO (KEMEROVO REGION, RUSSIA)

Известия высших учебных заведений: Геология и разведка, 2018
A new data on the geological structure, conditions of formation and faunal composition of the Early Cretaceous site of the terrestrial vertebrates by Shestakovo village (Kemerovo Region, Western Siberia) has been presented.The consolidated geological ...
A. V. Podlesnov, B. I. Morkovin, E. N. Maschenko   +2 more
doaj   +1 more source

An initial event in insect innate immune response: structural and biological studies of interactions between β-1,3-glucan and the N-terminal domain of β-1,3-glucan recognition protein [PDF]

, 2013
In response to invading microorganisms, insect β-1,3-glucan recognition protein (βGRP), a soluble receptor in the hemolymph, binds to the surfaces of bacteria and fungi and activates serine protease cascades that promote destruction of pathogens by means
Amzel L. M., An C., Barral P., Boraston A. B., Brünger A. T., Buchon N., Cavanagh C., Clore G. M., Cornilescu G., Daisuke Takahashi, David VanderVelde, Delaglio F., Deslandes Y., Fabrick J. A., Fabrick J. A., Goddard T. D., Gottar M., Handa N., Hiromasa Y., Hiromasa Y., Hrmova M., Huaien Dai, Jeffrey A. Fabrick, Jiang H., Kanagawa M., Kim Y. S., Laughton A. M., Lim J. H., Ma C., Matskevich A. A., Michael R. Kanost, Mishima Y., Ochiai M., Okuyama K., Peng J. W., Perkins S. J., Ramaswamy Krishnamoorthi, Roh K. B., Schachman H. K., Takahasi K., Wang Y., Weis W. I., Wiseman T., Wishart D. S., Yasuaki Hiromasa, Young S. H.   +45 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Insights into the impacts of inflow discharge variation on cross-sectional topography in the upper neck area of a laboratory-scale subaerial delta from SWJ–LSTM simulations

International Journal of Sediment Research
Rivers significantly influence delta morphology and sedimentation patterns. However, the dynamic effects of rivers on the upper neck areas of subaerial deltas, which are the complex zones connecting main channels to distributary networks, remain ...
Xiaolong Song, Haijue Xu, Yuchuan Bai
doaj   +1 more source

Slow sedimentation and deformability of charged lipid vesicles [PDF]

, 2013
The study of vesicles in suspension is important to understand the complicated dynamics exhibited by cells in vivo and in vitro. We developed a computer simulation based on the boundary-integral method to model the three dimensional gravity-driven ...
Gay, Guillaume, Gonzalez-Mancera, Andres, Leidy, Chad, Suarez, Ivan Rey, Tellez, Gabriel   +4 more
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Analytical simulation of meander morphology from equilibrium to long-term evolution: Impacts of channel geometry and vegetation-induced coarsening

International Journal of Sediment Research
This study introduces an innovative approach to modeling meandering river morphology, integrating and investigating the effects of geometric characteristics and vegetation-induced channel coarsening. The developed comprehensive framework combines several
Yanjie Sun, Xiaolong Song, Zhi Li, Haijue Xu, Yuchuan Bai   +4 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Multi-field coupling continuum numerical method for exploiting CH4 by CO2 replacement in deep-sea formation

Yantu gongcheng xuebao
The extraction method that induces hydrate dissociation may deteriorate the mechanical properties of methane hydrate bearing sediments (MHBS), potentially leading to a series of significant disasters.
JIANG Mingjing 1 , LI Ziyu 1, LI Chengchao 1, 2, JIANG Pengming 1
doaj   +1 more source