Results 81 to 90 of about 807,294 (385)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

A study of a quasilinear model of the particles of a suspension that are aggregated and settled in an inhomogeneous field

Visnik Harkivsʹkogo Nacionalʹnogo Universitetu im. V.N. Karazina. Cepiâ Matematika, Prikladna Matematika i Mehanika, 2020
The mathematical model of the sedimentation process of suspension particles is usually a quasilinear hyperbolic system of partial differential equations, supplemented by initial and boundary conditions.
Natalya Kizilova, Sergii Poslavskyi, Vitaliia Baranets   +2 more
doaj   +1 more source

Erythrocyte sedimentation rate and C-reactive protein.

Australian Prescriber, 2015
C-reactive protein is a better indicator of inflammation than the erythrocyte sedimentation rate. It is more sensitive and responds more quickly to changes in the clinical situation.
M. Harrison
semanticscholar   +1 more source

Sedimentation, trapping, and rectification of dilute bacteria [PDF]

, 2009
The run-and-tumble dynamics of bacteria, as exhibited by \textit{E. coli}, offers a simple experimental realization of non-Brownian, yet diffusive, particles. Here we present some analytic and numerical results for models of the ideal (low-density) limit
Cates, M. E., Tailleur, J.
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Assessing Differences in Groundwater Hydrology Dynamics Between In Situ Measurements and GRACE-Derived Estimates via Machine Learning: A Test Case of Consequences for Agroecological Relationships Within the Yazoo–Mississippi Delta (USA)

Hydrology
In situ groundwater monitoring is critical for irrigated agroecosystems and informs land cover changes. Yet, such data can pose management challenges and confound agroecological relationships.
Lucas J. Heintzman, Zahra Ghaffari, Abdel R. Awawdeh, Damien E. Barrett, Lance D. Yarbrough, Greg Easson, Matthew T. Moore, Martin A. Locke, Hakan I. Yasarer   +8 more
doaj   +1 more source

Dynamical demixing of a binary mixture under sedimentation

, 2018
We investigate the sedimentation dynamics of a binary mixture, the species of which differ by their Stokes coefficients but are identical otherwise. We analyze the sedimentation dynamics and the morphology of the final deposits using Brownian dynamics ...
Araujo, N. A. M., Braz, V. C., da Gama, M. M. Telo, Nunes, A. S.   +3 more
core  

Coastal oceanography and sedimentology in New Zealand, 1967-91. [PDF]

, 1992
This paper reviews research that has taken place on physical oceanography and sedimentology on New Zealand's estuaries and the inner shelf since c. 1967.
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core   +2 more sources

Researches on sedimentation [PDF]

Geological Society of America Bulletin, 1920
Purpose of this Symposium The purpose of this symposium is not to give an inventory of present information on sedimentation, nor is it to lay before you the definite solution of specific problems; but it is rather to discuss certain needs in the light of what we now know, and to consider ways and means of filling those needs.
openaire   +3 more sources