Results 81 to 90 of about 2,362,291 (310)

Seed weight variation of wyoming sagebrush in Northern Nevada [PDF]

, 2005
Seed size is a crucial plant trait that may potentially affect not only immediate seedling success but also the subsequent generation. We examined variation in seed weight of Wyoming sagebrush (Artemisia tridentata ssp. wyomingensis Beetle and Young), an
Busso, Carlos Alberto, Perryman, Barry L.   +1 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A multi-resolution systematically improvable quantum embedding scheme for large-scale surface chemistry calculations

Nature Communications
Predictive simulation of surface chemistry is critical in fields from catalysis to electrochemistry and clean energy generation. Ab-initio quantum many-body methods should offer deep insights into these systems at the electronic level but are limited by ...
Zigeng Huang, Zhen Guo, Changsu Cao, Hung Q. Pham, Xuelan Wen, George H. Booth, Ji Chen, Dingshun Lv   +7 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Relationship between seed harvesting method and seed physiological quality for a number of Pioneer maize hybrids [PDF]

, 2012
The seed germination and seed vigor of eight Pioneer Hi-Bred maize hybrids were evaluated immediately after harvesting and a year later. The aim was to determine whether the seed showed loss of germination and vigor when shelled mechanically.
Anda, Angéla, Berzy, Tamás, Ertsey, Katalin, Varga, Péter   +3 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Development and initiation of a preceptor program to improve midwifery and nursing clinical education in sub-saharan Africa: protocol for a mixed methods study

BMC Nursing
Background Expanding the quality and quantity of midwifery and nursing clinical preceptors is a critical need in many sub-Saharan educational settings to strengthen students’ clinical learning outcomes, and ultimately to improve maternal and child ...
Brittney van de Water, Kelsey Renning, Anda Nyondo, Mustapha Sonnie, Ashley H. Longacre, Helen Ewing, Mary Fullah, Lignet Chepuka, Julie Mann   +8 more
doaj   +1 more source

Seed transmission of Carlavirus vignae (Cowpea mild mottle virus): a hidden driver of veinal necrosis and bud blight disease in soybean (Glycine max) in India

Frontiers in Microbiology
A comprehensive investigation was conducted to determine the seed transmission potential of cowpea mild mottle virus (CPMMV) associated with veinal necrosis and bud blight (VNB) disease in soybean (Glycine max) under Indian agroecological conditions ...
Dhruva Nitin Bhagwatkar, Nagamani Sandra, Ankita Tripathi, Garima Dalal, Sharankumar Kesaratagi, Manisha Saini, Sandeep Kumar Lal, Sanjay Kumar Lal   +7 more
doaj   +1 more source

Sucrase in immobilized cells of Cucumis sativus L.

Horticultural Science, 2002
Cell suspension cultures of Cucumis sativus L. - cucumber were permeabilized by Tween, hexadecyltri-methylammonium bromide, hexadecylpyridiniumbromide ethanol and/or immobilized by glutaraldehyde.
S.I. Ignatova, L.M. Kušč, L. Bilisics, L. Trinh, N.N. Tiuliaeva, M.G. Sedova   +5 more
doaj   +1 more source