Results 101 to 110 of about 188,409 (303)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Manipulation of seed coat content for increasing oil content via modulating BnaMYB52 in Brassica napus

open access: yesCell Reports
Summary: Seed oil is synthesized in the embryo, which is surrounded by the seed coat. However, the genetic and molecular mechanisms of how seed coat development affects seed oil content (SOC) remains less studied.
Jiang Ye   +12 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

MÉTODOS PARA SUPERAÇÃO DA DORMÊNCIA EM SEMENTES DE Garcinia gardneriana (Planch. & Triana) Zappi

open access: yesCiência Florestal, 2018
Garcinia gardneriana is a native tree species of the Atlantic Forest biome with commercial potential, industrial application, medicinal, ornamental and timber, which seeds have difficulties on germination.
Ana Patrícia Rocha   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Permeabilitas dan Perkecambahan Benih Aren (Arenga Pinnata (Wurmb.) Merr.) [PDF]

open access: yes, 2009
The characteristics of seed coat delay the germination of sugar palm seeds. A research was carried out to investigate the permeability of sugar palm seeds and accelerate the germination. The research consists of four experiments with purposes: 1.
Soemardi, I. (Issirep)   +3 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

The relationship between seed coat color and seed quality in watermelon Crimson sweet

open access: yesHorticultural Science, 2010
This work was carried out to determine the relationship between seed coat color and seed quality in Crimson sweet watermelon. Seed lots (1, 2, 3, and 4) were prepared taking into consideration seed coat colors in fresh seeds with naked eye.
K. Mavi
doaj   +1 more source

Pengaruh Perlakuan Pencelupan dan Perendaman terhadap Perkecambahan Benih Sengon (Paraserianthes Falcataria L.) [PDF]

open access: yes, 2013
In developing productive forests, seeds play a crucial role. The seeds of forests tree have physical condition of hard seed coat, especially Leguminoceae family.
Kaya, E. (Elizabet)   +2 more
core  

Organic Corn Seed Coat Treatments

open access: yes, 2007
Introduction Organic seed treatments have been limited in organic production, until recently. Agricoat Natural IITM, is reported to be “an organic liquid biological seed treatment applied as a seed film coating and formulated with beneficial microbes, macro and micro nutrients, amino acids, organic acids, enzymes, proteins, vitamins, and minerals ...
Delate, Kathleen   +2 more
openaire   +3 more sources

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