Results 41 to 50 of about 1,092,233 (309)

Association Studies and Legume Synteny Reveal Haplotypes Determining Seed Size in Vigna unguiculata. [PDF]

open access: yes, 2013
Highly specific seed market classes for cowpea and other grain legumes exist because grain is most commonly cooked and consumed whole. Size, shape, color, and texture are critical features of these market classes and breeders target development of ...
Cisse, Ndiaga   +7 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Evaluation of Priming Techniques for Enhancement of Maize Inbred Line Seed Germination Parameters

open access: yesInternational Journal of Agronomy
Due to inadequate germination, emergence, and seedling stand establishment of inbred lines, hybrid seed multiplication results in poor performance and nonuniform seedlings in the field.
Getahun Bekele   +2 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

High Nitrogen Fertilization Decreases Seed Weight but Increases Longevity in Tomato Seeds

open access: yesHorticulturae, 2022
Nitrogen fertilization is a key practice in agriculture and its effects on yield and quality of most commodity products are widely known. However, the response of seed production to N fertilization, especially with regard to its effects on seed quality ...
Javier Sánchez   +2 more
doaj   +1 more source

Opportunities in Tajikistan to breed wheat varieties resistant to seed-borne diseases and improved baking quality [PDF]

open access: yes, 2013
Wheat seed-borne diseases and options for improving baking quality of wheat, as well as the role of genotypes for breeding to achieve high yield and quality are the key issues discussed in this introductory paper.
Husenov, Bahromiddin
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

The need for a supply of high quality organic vegetable seeds [PDF]

open access: yes, 2006
Production of high quality organic vegetable seeds encounters several challenges. Research is performed to support seed companies in producing vigorous and healthy organic vegetable seeds.
Groot, S.P.C.   +7 more
core   +2 more sources

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