Results 101 to 110 of about 1,762,405 (367)
Vector seeds: An extension to spaced seeds
AbstractWe present improved techniques for finding homologous regions in DNA and protein sequences. Our approach focuses on the core regions of a local pairwise alignment; we suggest new ways to characterize these regions that allow marked improvements in both specificity and sensitivity over existing techniques for sequence alignment.
Daniel G. Brown+2 more
openaire +2 more sources
Can the North Sea Still Save Europe? [PDF]
In the 1980s and 1990s the North Sea emerged as a key non-OPEC oil producing province. Yet today overall production is declining, in both the British and Norwegian sectors and the big oil companies and investors are losing interest in what they now see ...
Carole Nakhle
core
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Effects of Marquandomyces marquandii SGSF043 on Maize Growth Promotion and Soil Enzyme Activity
In order to further clarify the growth-promoting effect of the non-core Metarhizium sp. Marquandomyces marquandii on plants, M. marquandii SGSF043, which was obtained via pre-screening in the laboratory, was selected as a test strain and the seed soaking
Xu Zheng+4 more
doaj +1 more source
An Empirical Analysis of Energy Demand in Namibia [PDF]
Using a unique database of end-user local energy data and the recently developed Autoregressive Distributed Lag (ARDL) bounds testing approach to cointegration, we estimate the long-run elasticities of the Namibian energy demand function at both ...
Glauco De Vita+2 more
core
Fast tuneable InGaAsP DBR laser using quantum-confined stark-effect-induced refractive index change [PDF]
We report a monolithically integrated InGaAsP DBR ridge waveguide laser that uses the quantum-confined Stark effect (QCSE) to achieve fast tuning response.
Cannard, P+5 more
core +1 more source
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy+12 more
wiley +1 more source
Asymmetric Price Responses and the Underlying Energy Demand Trend: Are they Substitutes or Complements? Evidence from Modelling OECD Aggregate Energy Demand [PDF]
A number of energy demand studies have considered the importance of modelling Asymmetric Price Responses (APR), for example, the often-cited work of Gately and Huntington (2002). Griffin and Schulman (2005) questioned the asymmetric approach arguing that
David C Broadstock+4 more
core
Incentives and constraints for the use of organic seeds in organic farming: example of Capsicum annuum seeds in the Netherlands and Spain [PDF]
The EU legislation on organic farming was aimed at forcing the use of organic seeds in organic production. However, there are striking differences in its implementation across the EU and the use of organic seeds is still sparse.
Brühl, Katharina
core +2 more sources
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen+6 more
wiley +1 more source