Results 101 to 110 of about 1,559,015 (310)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Critical Evaluation of the Cgrain Value™ as a Tool for Rapid Morphometric Phenotyping of Husked Oat (Avena sativa L.) Grains

open access: yesSeeds
Mechanised non-contact, non-destructive imaging methodologies have revolutionised plant phenotyping, increasing throughput well beyond what was possible using traditional manual methods.
David Evershed   +5 more
doaj   +1 more source

Modelling Underlying Energy Demand Trends and Stochastic Seasonality: An Econometric Analysis of Transport Oil Demand in the UK and Japan [PDF]

open access: yes
This paper demonstrates the importance of adequately modelling the Underlying Energy Demand Trend (UEDT) and seasonality when estimating transportation oil demand for the UK and Japan. The structural time series model is therefore employed to allow for a
Lester C Hunt, Yasushi Ninomiya
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Effect of Melatonin on Germination and Seedling Growth in Aging Seeds or under Drought Conditions

open access: yesSeeds
Seed germination (GS) and seedling growth are vital plant stages that can be affected by stresses such as drought and aging, which cause deterioration and reduce seed viability.
Isabel García-Cánovas   +4 more
doaj   +1 more source

What drives the change in UK household energy expenditure and associated CO2 emissions? Implication and forecast to 2020 [PDF]

open access: yes
Given the amount of direct and indirect CO2 emissions attributable to UK households, policy makers need a good understanding of the structure of household energy expenditure and the impact of both economic and non-economic factors when considering ...
Lester C Hunt, Mona Chitnis
core  

Sowing Organic Seeds [PDF]

open access: yes, 2012
There is a growing realisation that only the adoption of ecological and sustainable farming practices can reverse the declining trend in farm productivity in the state of West Bengal, India. The paper is on how a small holding (3.8 acres) family farm in
Roy, Sabyasachi
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Application of Mealworm Frass in Organic Seedling Production of Allium cepa L., Beta vulgaris L., and Brassica rapa L.

open access: yesSeeds
Horticulture is mainly based on transplanting seedlings produced by specialized nurseries. The recent European authorization of frass in organic farming presents new opportunities for the development of organic seedling production. Frass, a by-product of
Ferdinando Baldacchino, Flutura Lamaj
doaj   +1 more source

Transportation Oil Demand Consumer Preferences and Asymmetric Price Responses: Some UK Evidence [PDF]

open access: yes
The aim of this paper is to (i) establish the role of asymmetric price decompositions in UK road transportation fuel demand, (ii) make explicit the impact of the underlying energy demand trend and (iii) disaggregate the estimation for gasoline and diesel
Alan Collins   +2 more
core  

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