Results 81 to 90 of about 2,973,774 (400)

An Empirical Analysis of Energy Demand in Namibia [PDF]

Using a unique database of end-user local energy data and the recently developed Autoregressive Distributed Lag (ARDL) bounds testing approach to cointegration, we estimate the long-run elasticities of the Namibian energy demand function at both ...
Glauco De Vita, Klaus Endresen, Lester C. Hunt   +2 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Food Superstores, Food Deserts and Traffic Generation in the UK: A Semi-Parametric Regression Approach [PDF]

This study contributes another route towards explaining and tackling ‘food desert’ effects. It features the estimation of a (semi-parametric) trip attraction model for food superstores in the UK using a composite dataset.
Alan Collins, Colin Black, David C. Broadstock, Lester C. Hunt   +3 more
core  

Fast tuneable InGaAsP DBR laser using quantum-confined stark-effect-induced refractive index change [PDF]

, 2007
We report a monolithically integrated InGaAsP DBR ridge waveguide laser that uses the quantum-confined Stark effect (QCSE) to achieve fast tuning response.
Cannard, P, Gwilliam, R, Pantouvaki, M, Renaud, CC, Robertson, MJ, Seeds, AJ   +5 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Field Evaluation of Salt Stress and Fertilization Effects (Organic and Inorganic) on Seed Yield, Proximate Seed Composition, Seed Elemental Composition and Protein Content in Fenugreek

Seeds
The chemical quality of fenugreek seeds is a critical factor influencing their nutritional value, medicinal properties, and suitability for agricultural and industrial applications, making it essential to evaluate their biochemical composition and ...
Antigolena Folina, Aspasia Efthimiadou, Panteleimon Stavropoulos, Antonios Mavroeidis, Ioanna Kakabouki, Eleni Tsiplakou, Dimitrios Bilalis   +6 more
doaj   +1 more source

GRAPE SEED EXTRACT VERSUS CAPTOPRIL IN AMELIORATING 5-FLUOROURACIL-INDUCED NEPHROTOXICITY IN ADULT MALE ALBINO RATS: BIOCHEMICAL, HISTOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY [PDF]

, 2020
Wesam Abd El-Salam Abd El-Wahab, Amal Abd El-Majid Ahmed, Mona Mohamed Abd Elgalil   +2 more
openalex   +1 more source

Optimal sliding scale regulation: An application to regional electricity distribution in England and Wales [PDF]

This paper examines optimal price (i.e. ‘sliding scale’) regulation of a monopoly when productivity and managerial effort are not observed. We show how to operationalise this model of incentive regulation and use actual data from electricity distribution
David Hawdon, Lester C. Hunt, Neil Rickman, Paul Levine   +3 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Seedling Emergence and Soil Seedbank Persistence of the Invasive Azadirachta indica A. Juss

Seeds
Azadirachta indica (Neem tree) has become widely naturalised and invasive across many countries and regions including northern Australia. To aid management of A.
Simon J. Brooks, Faiz F. Bebawi, Dannielle A. Brazier, Kirsty L. Gough, Shane D. Campbell   +4 more
doaj   +1 more source