Results 11 to 20 of about 108 (75)

The effect of peptide anxiolytic selank on cognitive impairment induced by acute alcohol in adolescent rats [PDF]

Фармакокинетика и Фармакодинамика, 2019
Nadorova AV, Chernyakova IV, Kolik LG FSBI «Zakusov Institute of Pharmacology», Moscow Resume. Background. Numerous experimental and clinical data confirm the vulnerability of the adolescent brain to ethanol and the long-term cognitive effects of acute ...
Anna Nadorova, Irina Chernyakova, Larisa Kolik   +2 more
doaj   +4 more sources

Structural transformations of thermal burn wounds in rats under the influence of Semax and Selank neuropeptides [PDF]

Фармация и фармакология (Пятигорск), 2020
The morphological features of the skin of rats under the stress exposure, such as burn injury and against the background of the correction by the drugs of the peptide structure, have been studied.The aim of the study was to investigate the regulatory ...
A. K. Azhikova, B. V. Feldman, A. A. Andreeva, D. D. Teply, M. A. Samotrueva, N. F. Myasoedov   +5 more
doaj   +2 more sources

EFFECTS OF PEPTIDE SELANK ON OXIDATIVE STRESS IN THE BRAIN AND THIN INTESTINE OF WHITE RATS ON EXPERIMENTAL MODEL OF TRAUMATIC BRAIN INJURY

Сибирский научный медицинский журнал, 2019
Effects of glyproline-containing peptide Selank on oxidative stress parameters in the brain and thin intestine were studied. Material and methods. Traumatic brain injury (TBI) was induced in rats by a shock model (weight drop method).
M. Yu. Fleyshman, I. V. Tolstenok, A. A. Innokent’ev   +2 more
doaj   +2 more sources

GLYPROLINES AS MODULATORS OF IMMUNOREACTIVITY WITHIN CONDITIONS OF “SOCIAL” STRESS [PDF]

Фармация и фармакология (Пятигорск), 2019
The most important direction in the development of modern medical science is the study of protective, compensatory and pathological reactions of the organism that occur in response to various stress factors.The aim of the study is the subsequent ...
M. A. Samotrueva, A. L. Yasenyavskaya, O. A. Bashkina, N. F. Myasoedov, L. A. Andreeva   +4 more
doaj   +2 more sources

THE PERSPECTIVES OF DEVELOPMENT OF NEW PEPTIDE PREPARATIONS FOR CLINICAL USE WHICH HAVE ANTI-INFECTION AND IMMUNE-MODULATING ACTIVITY [PDF]

Инфекция и иммунитет, 2014
. The aim of current work is to study influence of peptides in vitro and in vivo on cytokines synthesis (IFNα, IFNγ, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12, IL-18, TNFα) on the level of their transcription and production.
L. A. Andreeva, M. V. Mezentseva, A. N. Narovlianskiy, I. Ju. Nagaev, I. M. Shapoval, V. E. Scherbenko, L. I. Russu, N. F. Miasoedov   +7 more
doaj   +2 more sources

Modulation of the Surgical Stress Response in the Early Postoperative Period After Radical Nephrectomy as the Core of the Nephroprotective Strategy

Инновационная медицина Кубани
Background: One of the most important problems in medicine today is prevention of chronic kidney disease development and progression in patients who underwent radical nephrectomy.
Igor S. Shormanov, Maxim V. Kosenko, Dmitry N. Shchedrov, Christina A. Sokolova, Sergei A. Zhigalov, Andrey S. Soloviev, Magomed I. Azizov   +6 more
doaj   +2 more sources

Optimization of the treatment of anxiety disorders with selank

, 2020
Objective. To compare the efficacy and tolerability of monotherapy with phenazepam to complex treatment with the peptide preparation selank and phenazepam in patients with anxiety disorders. Material and methods.
Gushanskaya E.V., Myasoedov N.F., Chobanu I.K., Medvedev V.E., Kost N.V., Sokolov O.Y., Ter-Israelyan A.Y., Tereshchenko O.N.   +7 more
core   +2 more sources

The experimental study of the immunomodulating action of Semax and Selank on the model of „social” stress

European Pharmaceutical Journal, 2022
This study is devoted to the experimental study of the immunocorrecting action of Semax (Met-Glu-His-Phe-Pro-Gly-Pro) and Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) on the model of “social” stress formed as a result of sensory contact and inter-confrontation ...
Yasenyavskaya A.L., Samotrueva M.A., Myasoedov N.F., Andreeva L.A.   +3 more
doaj   +1 more source

The effectiveness of selank in the treatment of adjustment disorder [PDF]

, 2018
Background Adjustment disorder (AD) is one of the most common mental disorders. Considering the social and economic situation in Ukraine at present, in almost 50% of the population, there are non-psychotic mental health disorders, and this number ...
Verbenko, Viktoriya, Viktoriya Verbenko, Verbenko, Georgiy, Georgiy Verbenko   +3 more
core   +1 more source

Role of Semax and Selank neuropeptides in modulating cell-mediated immunity in the setting of skin burn injury

RUDN Journal of Medicine
Relevance. The work describes the results of neuropeptide compounds Semax and Selank in modulating disorders of the cellular link of immunity under experimental burn exposure. The aim — to study the effect of Semax and Selank on the number of white blood
Alfiya K. Azhikova, Marina A. Samotrueva, Lyudmila A. Andreeva, Nikolay F. Myasoedov   +3 more
doaj   +1 more source