Results 61 to 70 of about 103 (78)

POST-COVID SYNDROME, POSSIBILITIES FOR THERAPY OF ASTHENIC DISORDERS WITH SELANK

Vrach
Post-COVID syndrome develops after a COVID-19 infection, and is also observed in cases of mild or asymptomatic course of the disease. The most common symptoms of bridge syndrome are asthenia and decreased performance, with further development of cognitive deficit. Taking into account the leading role of immune disorders in the pathogenesis of COVID-19,
M. Pogodina, E. Nikiforova
openaire   +1 more source

Changes in the Transcription Profile of the Hippocampus in Response to Administration of the Tuftsin Analog Selank

Neuroscience and Behavioral Physiology, 2014
We describe here our studies of the effects of single doses and courses of the synthetic tuftsin analog Selank (a peptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro) at a dose of 200 μg/kg on the transcription profile of rat hippocampal cells using a cDNA microarray method.
T. A. Kolomin, T. Yu. Agapova, Ya. V. Agniullin, S. I. Shram, M. I. Shadrina, P. A. Slominskii, S. A. Limborskaya, N. F. Myasoedov   +7 more
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Combined Action of Benzodiazepine Tranquiizers and the Peptide Anxiolytic Selank on BALB/с Mice

Нейрохимия / Neurochemical Journal
Currently, the most common anxiolytic drugs are benzodiazepine tranquilizers, whose therapeutic effect is mediated by interaction with the allosteric binding site on GABA receptors. Despite the high efficiency of benzodiazepines, they are characterised by side effects associated with the sedative and muscle relaxant action.
N. V. Kost, O. Yu. Sokolov, S. A. Zozulya, N. F. Myasoedov   +3 more
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[Transcriptome alteration in hippocampus under the treatment of tuftsin analog Selank].

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 2014
The effect of single and course administration of Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) in the dose 200 microg/kg on the rat hippocampus transcriptional profile were studied using cDNA microarray technology. It was shown that mRNA levels of 36 genes changed more than 2-fold after a single intranasal Selank administration, and 20 genes--after course ...
T A, Kolomin, T Iu, Agapova, Ia V, Agniullin, S I, Shram, M I, Shadrina, P A, Slominskiĭ, S A, Limborskaia, I F, Miasoedov   +7 more
openaire   +1 more source

[A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2014
Objective. To study the efficacy and tolerability of the new anxyolytic peptide selank in comparison with phenazepam. Material and methods. A comparative study of the anxiolytic effect and tolerability of selank and phenazepam was carried out in 60 patients with phobic-anxiety- and somatoform disorders (F40.2-9, F41.1-9, F45.0-1 by ICD-10) were ...
V E, Medvedev, O N, Tereshchenko, A Iu, Israelian, I K, Chobanu, N V, Kost, O Iu, Sokolov, N F, Miasoedov   +6 more
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A New Property of the Synthetic Anxiolytic Selank and Its Derivatives

Doklady Biological Sciences, 2004
T S, Pavlov, G E, Samonina, L A, Andreeva, N F, Myasoedov, I P, Ashmarin   +4 more
openaire   +2 more sources

[Experimental hemorrhagic stroke: the study of neuropeptides (MIF, selank) in the intraperitoneal injection].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2010
The aim of this study was to examine Taftsin derivates--macrophage inhibitory factor (MIF, Thr-Lys-Pro) and heptapeptide selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) in the model of experimental intracerebral hemorrhage in rats. The double autologous blood injection in the basal nucleus was used as a model of intracerebral hemorrhage.
V I, Skvortsova, T V, Tvorogova, A I, Dubina, D V, Burenchev, L V, Gubskiĭ, L V, Stakhovskaia, O V, Povarova   +6 more
openaire   +1 more source

The cerebroprotective effects of Semax and Selank in primates at different types of neurosis

International Journal of Psychophysiology, 2008
T.N. Sollertinskaja, M.V. Shorochov, N.F. Myasoedov   +2 more
openaire   +1 more source

P.3.003 The effect of Selank on the seasonal depressed animal behaviour

European Neuropsychopharmacology, 2005
T.P. Semenova, I.I. Kozlovsky, A.V. Zuikov, E.N. Karavaev   +3 more
openaire   +1 more source

The temporary dynamics of inflammation-related genes expression under tuftsin analog Selank action

Molecular Immunology, 2014
Timur Kolomin, M I Shadrina, Petr A Slominsky   +2 more
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