ABSTRACT Background and Aims Extracellular vesicles (EVs) are nanoscale carriers, including exosomes, microvesicles, and apoptotic bodies, that mediate intercellular communication by transporting proteins, nucleic acids, lipids, and metabolites. They regulate immunity, tissue repair, and cell differentiation.
Kajal Kamra +7 more
wiley +1 more source
Flow Cytometric Profiling Reveals Platelet Dysfunction and Impaired Immune Communication in Acute and Chronic Cerebrovascular Disease. [PDF]
Shen CL +4 more
europepmc +1 more source
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
Prolactin-induced platelet activation and endothelial dysfunction in coronary artery disease: insights into PKC and TXA2 pathways. [PDF]
Li J +5 more
europepmc +1 more source
ABSTRACT Mesenchymal stromal cell‐derived extracellular vesicles (MSC‐EV) hold promising potential for immunomodulation and tissue regeneration, especially for treating ischemia‐reperfusion injury (IRI). However, their therapeutic use is hindered by challenges in tissue targeting and incomplete understanding of their functional mechanisms.
Marta Clos‐Sansalvador +11 more
wiley +1 more source
Fucosylation enhances CD34⁺ hematopoietic stem cell homing and longevity via E-selectin-mediated adhesion and signaling. [PDF]
Al-Amoodi AS +10 more
europepmc +1 more source
Understanding Sickle Cell Disease Endothelial Pathology Through the Lens of Liver Sinusoidal Endothelial Cells. [PDF]
Pradhan-Sundd T +2 more
europepmc +1 more source
[The selectins, selectin ligands and hemopoitic system].
openaire +2 more sources
ABSTRACT Introduction Research on immune checkpoint molecules is increasing, reflecting their critical role in cancer pathogenesis. While PD‐1, PD‐L1, and CTLA‐4 have been widely studied in head and neck cancers, outcomes remain unsatisfactory, highlighting the need for novel prognostic markers and therapeutic targets.
Fırat Tevetoğlu +2 more
wiley +1 more source
Insight to Neglected Biomarkers in COVID-19: A Comprehensive Narrative Review". [PDF]
Jalilian S, Bastani MN, Afsharzadeh F.
europepmc +1 more source

