Results 61 to 70 of about 2,135,140 (326)

Genetic Selection for Thermotolerance in Ruminants

open access: yesAnimals, 2019
Variations in climatic variables (temperature, humidity and solar radiation) negatively impact livestock growth, reproduction, and production. Heat stress, for instance, is a source of huge financial loss to livestock production globally. There have been
Richard Osei-Amponsah   +6 more
doaj   +1 more source

Impact of Genomic Prediction Model, Selection Intensity, and Breeding Strategy on the Long-Term Genetic Gain and Genetic Erosion in Soybean Breeding

open access: yesFrontiers in Genetics, 2021
Genomic-assisted breeding has become an important tool in soybean breeding. However, the impact of different genomic selection (GS) approaches on short- and long-term gains is not well understood. Such gains are conditional on the breeding design and may
Éder David Borges da Silva   +3 more
doaj   +1 more source

A Multi-task Deep Feature Selection Method for Brain Imaging Genetics [PDF]

open access: yesarXiv, 2021
Using brain imaging quantitative traits (QTs) to identify the genetic risk factors is an important research topic in imaging genetics. Many efforts have been made via building linear models, e.g. linear regression (LR), to extract the association between imaging QTs and genetic factors such as single nucleotide polymorphisms (SNPs).
arxiv  

Selection, inheritance, and the evolution of parent-offspring interactions

open access: yes, 2004
Very few studies have examined parent-offspring interactions from a quantitative genetic perspective. We used a cross-fostering design and measured genetic correlations and components of social selection arising from two parental and two offspring ...
Lock, Judith E.   +2 more
core   +1 more source

On the Effectiveness of Genetic Search in Combinatorial Optimization [PDF]

open access: yes, 1994
In this paper, we study the efficacy of genetic algorithms in the context of combinatorial optimization. In particular, we isolate the effects of cross-over, treated as the central component of genetic search. We show that for problems of nontrivial size
Carter, Bob, Park, Kihong
core   +3 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Perspectives from agriculture: advances in livestock breeding - implications for aquaculture genetics [PDF]

open access: yes, 2006
In this paper we present livestock breeding developments that could be taken into consideration in the genetic improvement of farmed aquaculture species, especially in freshwater fish.
Nguyen, N.H., Ponzoni, R.W.
core  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Morphological genetic markers for selection of broiler lines

open access: yesBrazilian Journal of Poultry Science, 2003
Two paternal broiler lines (LL and LLc, originated from the same stock in 1998) of Embrapa Suinos e Aves genetic program were used. Line LL had been selected for eight generations for rapid growth while LLc had been mated randomly, without selection, as ...
GS Schmidt   +4 more
doaj   +1 more source

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