Results 71 to 80 of about 1,388,322 (334)
Structure Selection of Polynomial NARX Models using Two Dimensional (2D) Particle Swarms
, 2018 The present study applies a novel two-dimensional learning framework (2D-UPSO) based on particle swarms for structure selection of polynomial nonlinear auto-regressive with exogenous inputs (NARX) models.
Hafiz, Faizal +3 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Inbreeding management and optimization of genetic gain with phenotypic and genomic selection in oil palm (Elaeis guineensis)[W776] [PDF]
, 2020 Oil palm breeding relies on reciprocal recurrent selection between two heterotic groups complementary for bunch number and average bunch weight. Given the long generation interval and the limited selection intensity imposed by the progeny tests currently
Cros, David +2 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Network assisted analysis to reveal the genetic basis of autism
, 2015 While studies show that autism is highly heritable, the nature of the genetic basis of this disorder remains illusive. Based on the idea that highly correlated genes are functionally interrelated and more likely to affect risk, we develop a novel ...
Lei, Jing, Liu, Li, Roeder, Kathryn
core +1 more source
Hybrid genetic algorithm for dual selection [PDF]
Pattern Analysis and Applications, 2007 Ce travail présente un algorithme génétique hybride pour résoudre le problème suivant : sélectionner dans une base d'exemples le sous ensemble qui présente la meilleure performance en classification avec le plus petit nombre d'attributs pour le plus grand nombre d'exemples.
Ros, F. +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Genetic Algorithm Based Feature Selection Technique for Electroencephalography Data
Applied Computer Systems, 2019 High dimensionality is a well-known problem that has a huge number of highlights in the data, yet none is helpful for a particular data mining task undertaking, for example, classification and grouping. Therefore, selection of features is used frequently
Ali Tariq +2 more
doaj +1 more source