Results 91 to 100 of about 191,946 (295)

Genome-Wide Signatures of Selection Reveal Genes Associated With Performance in American Quarter Horse Subpopulations

Frontiers in Genetics, 2018
Selective breeding for athletic performance in various disciplines has resulted in population stratification within the American Quarter Horse (QH) breed. The goals of this study were to utilize high density genotype data to: (1) identify genomic regions
Felipe Avila, James R. Mickelson, Robert J. Schaefer, Molly E. McCue   +3 more
doaj   +1 more source

Assessing Genomic Diversity and Signatures of Selection in Chinese Red Steppe Cattle Using High-Density SNP Array

Animals, 2023
Chinese Red Steppe Cattle (CRS), a composite cattle breed, is well known for its milk production, high slaughter rate, carcass traits, and meat quality.
Mingyue Hu, Hao Jiang, Weining Lai, Lulu Shi, Wenfeng Yi, Hao Sun, Chengzhen Chen, Bao Yuan, Shouqing Yan, Jiabao Zhang   +9 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Identification of Runs of Homozygosity Islands and Functional Variants in Wenchang Chicken

Animals, 2023
Wenchang chickens, a native breed in the Hainan province of China, are famous for their meat quality and adaptability to tropical conditions.
Shuaishuai Tian, Wendan Tang, Ziqi Zhong, Ziyi Wang, Xinfeng Xie, Hong Liu, Fuwen Chen, Jiaxin Liu, Yuxin Han, Yao Qin, Zhen Tan, Qian Xiao   +11 more
doaj   +1 more source

Variation and signatures of selection on the human face

Journal of Human Evolution, 2014
There has been much debate about why humans throughout the world differ in facial form. Previous studies of human skull morphology found levels of among-population differentiation that were comparable to those of neutral genetic markers, suggesting that genetic drift (neutral processes) played an important role in influencing facial differentiation ...
Guo, Jing, Tan, Jingze, Yang, Yajun, Zhou, Hang, Hu, Sile, Hashan, Agu, Bahaxar, Nurmamat, Xu, Shuhua, Weaver, Timothy D., Jin, Li, Stoneking, Mark, Tang, Kun   +11 more
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

miRNA Signatures in Sera of Patients with Active Pulmonary Tuberculosis. [PDF]

, 2013
Several studies showed that assessing levels of specific circulating microRNAs (miRNAs) is a non-invasive, rapid, and accurate method for diagnosing diseases or detecting alterations in physiological conditions.
Matteelli A., Ilaria C. Valente (488271), Valente I. C., Bosu R., Reither K., Valente, Ilaria C., Grace Mwangoka (488270), Aloi, Francesco, Sotgiu, Giovanni, Mwangoka Grace, Valente, Ilaria C, Delia Goletti, Klaus Reither, Roberta Bosu (488273), Grace Mwangoka, Luigi R Codecasa, Norbert Heinrich, Heinrich Norbert, Giovanni Sotgiu (16787), Ambrosi, Alessandro, Ntinginya, Elias N, Daniela M Cirillo, Bosu, Roberta, Miotto Paolo, Aloi Francesco, Goletti D., Ambrosi Alessandro, Klaus Reither (259897), Ntinginya, Elias N., Paolo Miotto (109897), Mwangoka G., Delia Goletti (78635), Miotto, Paolo, Luigi R. Codecasa (488274), Codecasa, Luigi R., Codecasa, Luigi R, Goletti, Delia, Sotgiu Giovanni, Roberta Bosu, Goletti Delia, Elias N Ntinginya, Norbis, Luca, Luca Norbis, Matteelli Alberto, Matteelli, Alberto, Norbis Luca, Sotgiu G., Valente Ilaria C., Aloi F., Alberto Matteelli, Norbert Heinrich (175590), Ambrosi A., Heinrich N., Cirillo D. M., Alessandro Ambrosi, Francesco Aloi (488276), Norbis L., Codecasa Luigi R., Luca Norbis (488272), Codecasa L. R., Reither, Klaus, Ilaria C Valente, Mwangoka, Grace, Cirillo, Daniela M., Heinrich, Norbert, Cirillo, Daniela M, Elias N. Ntinginya (349100), Reither Klaus, Miotto P., Giovanni Sotgiu, Bosu Roberta, Francesco Aloi, Paolo Miotto, Cirillo Daniela M., Alessandro Ambrosi (94298), Ntinginya Elias N., Alberto Matteelli (488275), Daniela M. Cirillo (109923), Ntinginya E. N.   +78 more
core   +1 more source

Genetic signatures of evolutionary rescue by a selective sweep [PDF]

Genetics, 2019
Abstract One of the most useful models in population genetics is that of a selective sweep and the consequent hitch-hiking of linked neutral alleles. While variations on this model typically assume constant population size, many instances of strong selection and rapid adaptation in nature may co-occur with complex ...
Osmond, Matthew M., Coop, Graham
openaire   +4 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Validation of selection signatures for coat color in the Podolica Italiana gray cattle breed

Frontiers in Genetics
Taurine and indicine gray cattle represent relevant livestock resources in many countries of the world. A gray coat color and pigmented skin, which are common in most of the gray cattle breeds, have been demonstrated to confer better adaptation to solar ...
Silvia Bruno, Giacomo Rovelli, Vincenzo Landi, Fiorella Sbarra, Andrea Quaglia, Fabio Pilla, Emiliano Lasagna, Elena Ciani   +7 more
doaj   +1 more source