Results 91 to 100 of about 179,723 (264)

Assessment of selective breeding effects and selection signatures in Qingyuan partridge chicken and its strains

Poultry Science
: Qingyuan partridge chicken (QYM) is a highly regarded native breed in China, highly esteemed for its exceptional breeding characteristics. However, the investigation into the selection signatures and its strains remains largely unexplored.
Shaofen Kong, Bolin Cai, Xiaojing Li, Zhen Zhou, Xiang Fang, Xin Yang, Danfeng Cai, Xuehui Luo, Suyin Guo, Qinghua Nie   +9 more
doaj   +1 more source

Novel and known signals of selection for fat deposition in domestic sheep breeds from Africa and Eurasia.

PLoS ONE, 2019
Genomic regions subjected to selection frequently show signatures such as within-population reduced nucleotide diversity and outlier values of differentiation among differentially selected populations.
Salvatore Mastrangelo, Hussain Bahbahani, Bianca Moioli, Abulgasim Ahbara, Mohammed Al Abri, Faisal Almathen, Anne da Silva, Ibrahim Belabdi, Baldassare Portolano, Joram M Mwacharo, Olivier Hanotte, Fabio Pilla, Elena Ciani   +12 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Feature Selection and Binarization for On-Line Signature Recognition [PDF]

, 2009
The representation of a biometric trait through a set of parametric features is commonly employed in many biometric authentication systems. In order to avoid any loss of useful information, large sets of features have been defined for biometric characteristics such as signature, gait or face.
Emanuele Maiorana, Patrizio Campisi, Alessandro Neri 0001   +2 more
openaire   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Selection signatures in Gir and Holstein cattle

Journal of Dairy Science
Natural and artificial selection leave footprints on the genome, known as selection signatures, that can indicate regions related to adaptive and economically important traits. The recurrent use of a limited number of sires and increased selection pressure may affect genetic diversity, potentially affecting long-term breeding programs.
Larissa G. Braga, Flávio S. Schenkel, Tatiane C.S. Chud, Julia L. Rodrigues, Bacem Saada, Marco.A. Machado, João C.C. Panetto, Marcos V.G.B. da Silva, Danísio P. Munari   +8 more
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source