Results 131 to 140 of about 3,585,940 (324)

Selection Signatures Analysis Reveals Genes Associated with High-Altitude Adaptation in Tibetan Goats from Nagqu, Tibet

open access: yesAnimals, 2020
Simple Summary In the process of domestication, goats have undergone long-term artificial and natural selection, leading to differences among goat breeds and leaving different selection traces on the genome.
Meilin Jin   +9 more
semanticscholar   +1 more source

Efficient signature selection tool for sense & react systems

open access: yes2016 13th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design (SMACD), 2016
Reconfigurable circuit design has become very important in the last decade for increasing the lifetime of CMOS circuits in deep sub-micron technologies. Sense & React approach is one of the reconfigurable design approaches, where degradation in a circuit performance is detected via sensor circuitry and a pre-established recovery operation is applied to
Afacan, Engin   +4 more
openaire   +3 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Exploring signature multiplicity in microarray data using ensembles of randomized trees [PDF]

open access: yes, 2011
A challenging and novel direction for feature selection research in computational biology is the analysis of signature multiplicity. In this work, we propose to investigate the eect of signature multiplicity on feature importance scores derived from tree-
Geurts, Pierre, Saeys, Yvan
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Identifying signatures of recent selection in Holstein cattle in the tropic

open access: yesRevista Colombiana de Ciencias Pecuarias, 2018
Background: Holstein cattle have undergone strong selection processes in the world. These selection signatures can be recognized and utilized to identify regions of the genome that are important for milk yield.
Juan C. Rincón   +2 more
doaj   +1 more source

Selection signatures in Canchim beef cattle. [PDF]

open access: yes, 2015
Selection signature (SS) was assessed in this study by means of the integrated haplotype score (iHS) method, which determines the decay of homozygosity in the surroundings of a core single nucleotide polymorphism (SNP) marker.
BUZANSKAS, M. E.   +6 more
core  

Rapid adaptation of a polygenic trait after a sudden environmental shift

open access: yes, 2017
Although a number of studies have shown that natural and laboratory populations initially well-adapted to their environment can evolve rapidly when conditions suddenly change, the dynamics of rapid adaptation are not well understood.
Jain, Kavita, Stephan, Wolfgang
core   +1 more source

High performance computation of landscape genomic models integrating local indices of spatial association [PDF]

open access: yes, 2014
Since its introduction, landscape genomics has developed quickly with the increasing availability of both molecular and topo-climatic data. The current challenges of the field mainly involve processing large numbers of models and disentangling selection ...
Bruford, Michael W.   +8 more
core   +2 more sources

Genome-wide scan for selection signatures reveals novel insights into the adaptive capacity in local North African cattle

open access: yesScientific Reports, 2020
Natural-driven selection is supposed to have left detectable signatures on the genome of North African cattle which are often characterized by the fixation of genetic variants associated with traits under selection pressure and/or an outstanding genetic ...
Slim Ben-Jemaa   +4 more
semanticscholar   +1 more source

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