Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Effect of zeolite topology and reactor configuration on the direct conversion of CO2 to light olefins and aromatics [PDF]
The direct transformation of CO2 into high-value-added hydrocarbons (i.e., olefins and aromatics) has the potential to make a decisive impact in our society. However, despite the efforts of the scientific community, no direct synthetic route exists today
Abou-Hamad, Edy +11 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Bimetallic Ni-Cu/SiO2 catalysts with different Cu loading (2–5 wt%) were developed for liquid phase selective hydrogenation of furfural to furfuryl alcohol.
Patcharaporn Weerachawanasak +5 more
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A comparative study on the jet loop reactor and continuos stirred tank reactor in the selective hydrogenation of palm olein (I.V.64) [PDF]
Jet Loop Reactor (JLR) was developed to improve the overall performance of hydrogenation processes. Nevertheless, the application of JLR in the palm oil and oleochemical industries in Malaysia is still very much sparse. A substantial amount of investment
Tea, Swee Sin
core
Designing organometallic compounds for catalysis and therapy [PDF]
Bioorganometallic chemistry is a rapidly developing area of research. In recent years organometallic compounds have provided a rich platform for the design of effective catalysts, e.g. for olefin metathesis and transfer hydrogenation.
Abraha Habtemariam +188 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Selective ensembles in supported palladium sulfide nanoparticles for alkyne semi-hydrogenation
Developing robust catalysts for alkyne semi-hydrogenation remains a challenge. Here, the authors introduce a scalable protocol to prepare crystal phase and orientation controlled Pd3S nanoparticles supported on carbon nitride, exhibiting unparalleled ...
Davide Albani +6 more
doaj +1 more source
Catalytic Performance of Ru/polymer Catalyst in the Hydrogenation of Furfural to Furfuryl Alcohol
Furfural (FF) is one of the main components of bio-oil obtained by the treatment of lignocellulose biomass. Furfural alcohol (FA) as the main product of the selective FF hydrogenation is a source of value-added chemicals.
Mikhail Sulman +8 more
doaj +1 more source

