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Selective Internal Radiation Therapy Dosimetry
Future Oncology, 2014Dosimetry is the calculation of radiation energy absorbed by tissue (measured in Grays [Gy]) as a result of exposure to indirect and direct ionizing radiation. The strength of a radioactive source is called its activity, which is defined as the rate at which the isotope decays over time.
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Selective Internal Radiation therapy
2008Primary and secondary liver tumours are common malignancies associated with unsatisfactory treatment and bad prognosis. Hepatocellular carcinoma (HCC) ranks among the 10 most common cancers worldwide and is the most common primary malignancy of the liver.
A. Al-Nahhas +4 more
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The Evidence for Resection Post-Selective Internal Radiation Therapy
Future Oncology, 2014Selective internal radiation therapy (SIRT) has become a well-established modality for the palliative treatment of primary and metastatic liver tumors. As a consequence of the growing experience with this treatment, research has recently focused on its potential as a component in the management of patients for curative treatment.
Benjamin, Garlipp, Christiane J, Bruns
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Optimizing the use of PET with Selective Internal Radiation Therapy
Future Oncology, 2014PET coupled with computed tomography (CT) is indicated for the management of patients undergoing selective internal radiation therapy (SIRT), both as an aid to treatment planning as well as for post-SIRT dosimetry and the assessment of the metabolic response.
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Selective Internal Radiation Therapy
2007The majority of primary and secondary malignant hepatic tumors are not suitable for surgical resection, which makes systemic chemotherapy treatments and/or local ablative therapies important components of intention-to-treat concepts or palliation. Tumor load and type of response determine the efficacy of these therapies.
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Selective internal radiation therapy: validation of intraoperative dosimetry.
Radiology, 1990In selective internal radiation (SIR) therapy of hepatic metastases, tumor vasculature is preferentially embolized with high-energy beta-emitting yttrium-90-labeled microspheres. To enable accurate estimation of the resultant absorbed radiation doses to tissues, an intraoperative beta detection probe is used to scan the liver surface.
M A, Burton +3 more
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Yttrium-90 Selective Internal Radiation Therapy
2017Yttrium-90 Selective internal radiation therapy is a growing part of the field of liver-directed radiation therapy. This technique involves the delivery of radioactive microbeads directly into liver tumors via the blood supply. There are presently two devices available to deliver Y90, with different techniques and clinical considerations for the two ...
D. Thor Johnson, Adam Leon Kesner
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Selective internal radiation therapy in patients with progressive neuroendocrine liver metastases
European Journal of Nuclear Medicine and Molecular Imaging, 2015To evaluate the safety and efficacy of selective internal radiation therapy (SIRT) in patients with unresectable liver metastases from neuroendocrine tumours (NETLMs).This retrospective study included 40 patients with progressive NETLMs (22 women, 18 men, mean age 61.6 years) who underwent SIRT with (90)Y-labelled resin microspheres.
Charlotte Ebeling, Barbier +4 more
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Hypertrophy in the Contralateral Lobe Post-Selective Internal Radiation Therapy
Future Oncology, 2014In patients with unilateral, primary and secondary liver tumors potentially amenable to curative resection, the need to perform an extended hepatectomy in order to affect a cure can often be hampered by insufficient liver volume in the future liver remnant (FLR).
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Treatment of Neuroendocrine Tumors with Selective Internal Radiation Therapy
2013The pathophysiology of neuroendocrine tumors (NET) is discussed and the differences in types of tumors within this broad category are highlighted. While carcinoid is the most common of the NETs, the general principles of treatment can be extrapolated to the NETs in general.
Douglas M. Coldwell +2 more
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