Results 201 to 210 of about 36,174 (249)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

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Stereotactic radiation therapy and selective internal radiation therapy for hepatocellular carcinoma

Cancer Radiotherapie: Journal De La Societe Francaise De Radiotherapie Oncologique, 2011
Recent technological advances allow precise and safe radiation delivery in hepatocellular carcinoma. Stereotactic body radiotherapy is a conformal external beam radiation technique that uses a small number of relatively large fractions to deliver potent doses of radiation therapy to extracranial sites. It requires stringent breathing motion control and
Laura Dawson, L A Dawson
exaly   +3 more sources

Selective internal radiation therapy in the management of primary and metastatic disease in the liver

British Journal of Hospital Medicine (London, England: 2005), 2021
Selective internal radiation therapy is a type of brachytherapy used to provide targeted radiotherapy, most commonly to treat primary or metastatic disease within the liver. This review outlines current clinical practice, dosimetric considerations, the pre-treatment workup and safety considerations before treatment.
Nadeem Shaida
exaly   +3 more sources

Y90 Selective Internal Radiation Therapy

Surgical Oncology Clinics of North America, 2015
Primary liver malignancies and liver metastases are affecting millions of individuals worldwide. Because of their late and advanced stage presentation, only 10% of patients can receive curative surgical treatment, including transplant or resection. Alternative treatments, such as systemic chemotherapy, ablative therapy, and chemoembolization, have been
Edward W, Lee, Avnesh S, Thakor, Bashir A, Tafti, David M, Liu   +3 more
openaire   +2 more sources

Selective internal radiation therapy: Distribution of radiation in the liver

European Journal of Cancer and Clinical Oncology, 1989
Selective internal radiation therapy for primary and secondary liver cancer involves the intra-hepatic arterial injection of microspheres containing yttrium-90. The microspheres become entrapped primarily in, and thus preferentially irradiate, tumour tissue.
M A, Burton, B N, Gray, P F, Klemp, D K, Kelleher, N, Hardy   +4 more
openaire   +2 more sources

Dose distribution following selective internal radiation therapy

International Journal of Radiation Oncology*Biology*Physics, 1991
Selective Internal Radiation Therapy is the intrahepatic arterial injection of microspheres labelled with 90Y. The microspheres lodge in the precapillary circulation of tumor resulting in internal radiation therapy. The activity of the 90Y injected is managed by successive administrations of labelled microspheres and after each injection probing the ...
R A, Fox, P F, Klemp, G, Egan, L L, Mina, M A, Burton, B N, Gray   +5 more
openaire   +2 more sources