Advanced Science, EarlyView.Combined inhibition of the WDR5 WIN pocket and HDAC activity converts SAHA‐induced hyperacetylation into a promoter state with reduced WDR5–COMPASS association and H3K4me3. MYC/E2F‐linked nascent transcription and biosynthetic recovery are suppressed, while apoptosis and senescence‐like features increase, resulting in sustained growth inhibition in ...
Jintian Song +8 more
wiley +1 more source
Biliary and respiratory complications after right hepatectomy for hepatocellular carcinoma following selective internal radiation therapy (SIRT): a retrospective case-control study. [PDF]
Hepatobiliary Surg NutrAl Taweel B +6 more
europepmc +1 more source
Habitat‐Specific Design Strategies for Untethered Soft Robots
Advanced Science, EarlyView.Habitat shapes the design of untethered soft robots. Across land, water, air, and living tissues, environmental constraints govern viable combinations of compliant structures, actuation mechanisms, and energy delivery. This review connects these constraints with robotic performance and identifies design principles for advancing adaptable, durable, and ...
Siyang Li +3 more
wiley +1 more source
Discordant patterns of anterior abdominal wall radiotracer accumulation in yttrium-90 selective internal radiation therapy: implications for pretherapeutic planning and posttreatment monitoring. [PDF]
Nucl Med CommunGong H +8 more
europepmc +1 more source
Advanced Science, EarlyView.A VDAP‐programmed liquid‐crystalline depot enables pH‐responsive postoperative immunotherapy for triple‐negative breast cancer. VDAP stabilizes a leakage‐resistant HII mesophase through peptide–lipid electrostatic assembly, whereas tumor acidosis unlocks the matrix and promotes graded topology remodeling toward a bicontinuous Im3̄m cubic phase for ...
Yan Yan +12 more
wiley +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo +3 more
wiley +1 more source
A novel triple-modality approach overcoming prohibitive hepatopulmonary shunt (HPS): Enabling yttrium-90 selective internal radiation therapy (Y90-SIRT) and subsequent curative resection in massive hepatocellular carcinoma (HCC). [PDF]
Radiol Case RepLuo Y, Lin Y.
europepmc +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao +5 more
wiley +1 more source
A Bioinspired Underwater Soft Robot for Active Intravesical Liquid Delivery and Mixing
Advanced Intelligent Systems, EarlyView.A bioinspired underwater soft robot is reported that integrates an elastic strain energy‐driven soft robotic pump with a programmable flexible magnetic valve, enabling remotely controlled, programmable, and sustained liquid release and mixing. This functionality is enabled by the synergistic integration of elastic strain energy‐driven pumping and ...
Jacob Katona +7 more
wiley +1 more source