Results 221 to 230 of about 89,275 (314)
Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö +8 more
wiley +1 more source
Selective serotonin reuptake inhibitors induce cardiac toxicity through dysfunction of mitochondria and sarcomeres. [PDF]
Shen Y +9 more
europepmc +1 more source
Aims Globally, Australia has the highest per capita consumption rate of pregabalin, commonly prescribed for neuropathic pain. Emerging evidence suggests pregabalin may be associated with the onset or recurrence of several potentially life‐threatening psychiatric events in some individuals.
Amy G. McNeilage +4 more
wiley +1 more source
Progress in the study of the effects of selective serotonin reuptake inhibitors (SSRIs) on the reproductive system. [PDF]
Feng Y, Qu X, Hao H.
europepmc +1 more source
Selective Serotonin Reuptake Inhibitors and Cosmetic Psychopharmacology: Ethical and Deontological Dilemmas [PDF]
DiPietro, Maria Luisa +2 more
core +2 more sources
From Struggling (With) Screening Tests to Mouse Models of Depression‐Relevant Neurobehavioral States
Abstract A major, serendipitous psychiatric discovery is monoamine‐transporter reuptake inhibition as an antidepressant mechanism of action. Chronic treatment with such antidepressants is efficacious, with onset requiring 1‐2 weeks, in many but by no means all patients with major depressive or another stress‐related neuropsychiatric disorder.
Christopher R. Pryce
wiley +1 more source

