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Understanding the molecular pharmacology of the serotonergic system : using fluoxetine as a model [PDF]
Objectives: Serotonin is a monoamine neurotransmitter that is widely distributed in the body and plays an important role in a variety of psychological and other body functions such as mood, sexual desire and function, appetite, sleep, memory and learning,
Mifsud, Janet, Sghendo, Lino
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Chirality of Modern Antidepressants: An Overview [PDF]
The majority of modern antidepressants (selective serotonin reuptake inhibitors and selective serotonin and norepinephrine reuptake inhibitors) have one or two centers of asymmetry in their structure; resulting in the formation of enantiomers which may ...
Monica Budău+4 more
doaj +1 more source
Experimental Pharmacological Research Regarding the Potential Antidepressant Activity Induced by Some Newly Synthesised Dibenzo[a,d]cycloheptene Compounds [PDF]
Background. Depression is a relatively frequent encountered mental disorder in the general population, affecting both the quality of the individual life and its ability to perform the social tasks; it is generally accepted that new studies related to ...
Junghină, Adrian+3 more
core +4 more sources
Serotonin and Noradrenaline Reuptake Inhibitors Improve Micturition Control in Mice [PDF]
Poor micturition control may cause profound distress, because proper voiding is mandatory for an active social life. Micturition results from the subtle interplay of central and peripheral components.
Antonio, Caretta+6 more
core +8 more sources
Neuropharmacological classification of antidepressant agents based on their mechanisms of action
The currently available clinical antidepressants can be classified into 13 different classes based on their mechanisms of action. These basic pharmacological concepts thoroughly elucidate and unravel the therapeutic actions and side effects of the wide ...
Olumuyiwa John Fasipe
doaj +1 more source
Millions of patients suffer from major depressive disorder (MDD), but many do not respond to selective serotonin reuptake inhibitor (SSRI) therapy. We used a pharmacometabolomics-informed pharmacogenomics research strategy to identify genes associated ...
Meenal Gupta+19 more
semanticscholar +1 more source
Duloxetine-induced rapid eye movement sleep behavior disorder: a case report
Background Tricyclic antidepressants and selective serotonin reuptake inhibitors have been reported to induce the symptoms of rapid eye movement (REM) sleep behavior disorder (RBD) or to exacerbate REM sleep without atonia.
Lu Tan+6 more
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Selective serotonin reuptake inhibitors for premenstrual syndrome [PDF]
This is a substantive update of a previous review. Severe premenstrual syndrome (PMS) affects between 3% to 5% of women of reproductive age. Severe PMS is classified under the Diagnostic and Statistical Manual of Mental Disorders as premenstrual dysphoric disorder (PMDD).
Patrick O'Brien+3 more
openaire +5 more sources
The data provided here related to our research article (Chen et al., 2016) [1]. We provide whole-brain intrinsic functional connectivity patterns in obsessive–compulsive disorder at resting-state [1].
Yunhui Chen+11 more
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Latest updates on the serotonergic system in depression and anxiety
Psychiatric disorders are among the leading causes of global health burden, with depression and anxiety being the most disabling subtypes. The two common disorders, depression and anxiety, usually coexist and are pathologically polygenic with complicated
Jianwen Lin+11 more
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