Results 41 to 50 of about 117,301 (397)

Understanding the molecular pharmacology of the serotonergic system : using fluoxetine as a model [PDF]

open access: yes, 2011
Objectives: Serotonin is a monoamine neurotransmitter that is widely distributed in the body and plays an important role in a variety of psychological and other body functions such as mood, sexual desire and function, appetite, sleep, memory and learning,
Mifsud, Janet, Sghendo, Lino
core   +1 more source

Chirality of Modern Antidepressants: An Overview [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2017
The majority of modern antidepressants (selective serotonin reuptake inhibitors and selective serotonin and norepinephrine reuptake inhibitors) have one or two centers of asymmetry in their structure; resulting in the formation of enantiomers which may ...
Monica Budău   +4 more
doaj   +1 more source

Experimental Pharmacological Research Regarding the Potential Antidepressant Activity Induced by Some Newly Synthesised Dibenzo[a,d]cycloheptene Compounds [PDF]

open access: yes, 2015
Background. Depression is a relatively frequent encountered mental disorder in the general population, affecting both the quality of the individual life and its ability to perform the social tasks; it is generally accepted that new studies related to ...
Junghină, Adrian   +3 more
core   +4 more sources

Serotonin and Noradrenaline Reuptake Inhibitors Improve Micturition Control in Mice [PDF]

open access: yes, 2015
Poor micturition control may cause profound distress, because proper voiding is mandatory for an active social life. Micturition results from the subtle interplay of central and peripheral components.
Antonio, Caretta   +6 more
core   +8 more sources

Neuropharmacological classification of antidepressant agents based on their mechanisms of action

open access: yesArchives of Medicine and Health Sciences, 2018
The currently available clinical antidepressants can be classified into 13 different classes based on their mechanisms of action. These basic pharmacological concepts thoroughly elucidate and unravel the therapeutic actions and side effects of the wide ...
Olumuyiwa John Fasipe
doaj   +1 more source

TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics

open access: yesMolecular Psychiatry, 2016
Millions of patients suffer from major depressive disorder (MDD), but many do not respond to selective serotonin reuptake inhibitor (SSRI) therapy. We used a pharmacometabolomics-informed pharmacogenomics research strategy to identify genes associated ...
Meenal Gupta   +19 more
semanticscholar   +1 more source

Duloxetine-induced rapid eye movement sleep behavior disorder: a case report

open access: yesBMC Psychiatry, 2017
Background Tricyclic antidepressants and selective serotonin reuptake inhibitors have been reported to induce the symptoms of rapid eye movement (REM) sleep behavior disorder (RBD) or to exacerbate REM sleep without atonia.
Lu Tan   +6 more
doaj   +1 more source

Selective serotonin reuptake inhibitors for premenstrual syndrome [PDF]

open access: yesCochrane Database of Systematic Reviews, 2002
This is a substantive update of a previous review. Severe premenstrual syndrome (PMS) affects between 3% to 5% of women of reproductive age. Severe PMS is classified under the Diagnostic and Statistical Manual of Mental Disorders as premenstrual dysphoric disorder (PMDD).
Patrick O'Brien   +3 more
openaire   +5 more sources

Data on the impact of SSRIs and depression symptoms on the neural activities in obsessive–compulsive disorder at rest

open access: yesData in Brief, 2016
The data provided here related to our research article (Chen et al., 2016) [1]. We provide whole-brain intrinsic functional connectivity patterns in obsessive–compulsive disorder at resting-state [1].
Yunhui Chen   +11 more
doaj   +1 more source

Latest updates on the serotonergic system in depression and anxiety

open access: yesFrontiers in Synaptic Neuroscience, 2023
Psychiatric disorders are among the leading causes of global health burden, with depression and anxiety being the most disabling subtypes. The two common disorders, depression and anxiety, usually coexist and are pathologically polygenic with complicated
Jianwen Lin   +11 more
doaj   +1 more source

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