Results 51 to 60 of about 117,301 (397)

The effects of antidepressants appear to be rapid and at environmentally relevant concentrations [PDF]

, 2015
The effects of antidepressants on wildlife are currently raising some concern because of an increased number of publications indicating biological effects at environmentally relevant concentrations (\u3c100 ng/L).
Fong, Peter P., Ford, Alex
core   +2 more sources

Consistent superiority of selective serotonin reuptake inhibitors over placebo in reducing depressed mood in patients with major depression

Molecular Psychiatry, 2015
The recent questioning of the antidepressant effect of selective serotonin reuptake inhibitors (SSRIs) is partly based on the observation that approximately half of company-sponsored trials have failed to reveal a significant difference between active ...
F. Hieronymus, J. Emilsson, Staffan Nilsson, Elias Eriksson   +3 more
semanticscholar   +1 more source

Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]

, 2004
Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C., Laakmann, G., Schule, C.   +2 more
core   +1 more source

Pharmacokinetics and Pharmacodynamics: A Comprehensive Analysis of the Absorption, Distribution, Metabolism, and Excretion of Psychiatric Drugs

Pharmaceuticals
The two main classifications of antidepressant medications are selective norepinephrine reuptake inhibitors (SNRIs) and selective serotonin reuptake inhibitors (SSRIs).
Zainab Zakaraya, Mohammad Abu Assab, Lina N. Tamimi, Nida Karameh, Mohammad Hailat, Laila Al-Omari, Wael Abu Dayyih, Omar Alasasfeh, Mohammad Awad, Riad Awad   +9 more
doaj   +1 more source

Endophenotypes and serotonergic polymorphisms associated with treatment response in obsessive-compulsive disorder

Clinics, 2012
OBJECTIVES: Approximately 40-60% of obsessive-compulsive disorder patients are nonresponsive to serotonin reuptake inhibitors. Genetic markers associated with treatment response remain largely unknown.
Fábio M. Corregiari, Márcio Bernik, Quirino Cordeiro, Homero Vallada   +3 more
doaj   +1 more source

Tratamento farmacológico do transtorno obsessivo-compulsivo

Brazilian Journal of Psychiatry, 2001
The pharmacotherapy for obsessive-compulsive disorder (OCD) has started with clomipramine, a potent non-selective serotonin reuptake inhibitor. Newer drugs that selectively inhibit serotonin reuptake (SSRIs) such as fluvoxamine, fluoxetine, paroxetine ...
Carla Marques
doaj   +1 more source

Extrapyramidal symptoms and antidepressants – A systematic review

Telangana Journal of Psychiatry
Selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, and tricyclic antidepressants have all been implicated, albeit to varying extents, in precipitating extrapyramidal symptoms.
Ankit Halder, Disha Maity, Satrajit Ghosal, Ashwini Lad   +3 more
doaj   +1 more source

Brain serotonin synthesis capacity in obsessive-compulsive disorder: effects of cognitive behavioral therapy and sertraline. [PDF]

, 2018
Cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitors (SSRIs) are both effective treatments for some patients with obsessive-compulsive disorder (OCD), yet little is known about the neurochemical changes related to these ...
Barsoum, Amir, Benkelfat, Chawki, Berney, Alexandre, Cottraux, Jean, Diksic, Mirko, Gravel, Paul, Leyton, Marco, Lissemore, Jennifer I, Nordahl, Thomas E, Pinard, Gilbert, Sibon, Igor, Sookman, Debbie   +11 more
core   +2 more sources

De‐Saturation of Single‐Atom Copper Catalysts for Accelerating Propargylic Substitution Reactions

Advanced Materials, EarlyView.
De‐saturation of copper‐based single‐atom catalysts (De‐sat SACs) are realized by a KOH‐mediated Joule thermal shock strategy. Benefiting from the under‐saturation coordination environment of single‐atom Cu center, De‐sat Cu SACs exhibit remarkable catalytic activity in propargylic substitution reactions, tolerating a broad range of nucleophiles (N–, C–
Qilong Cai, Yang Meng, Chao Wu, Wenjia Qu, Qiang Wang, Tan Li, Chengyi Liu, Jinxing Chen, Huihui Lin, Qian He, Yafei Zhao, Shibo Xi, Jiong Lu   +12 more
wiley   +1 more source

Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A meta-analysis of randomised controlled treatment trials [PDF]

, 2006
Small studies have shown positive effects from adding a variety of antipsychotic agents in patients with obsessive–compulsive disorder who are unresponsive to treatment with serotonin reuptake inhibitors. The evidence, however, is contradictory.
Carey, P, Denys, D, Fineberg, N, Premkumar, P, Seedat, S, Sivakumaran, T, Stein, DJ, Vythilingum, B, Westenberg, H   +8 more
core   +1 more source