Results 141 to 150 of about 1,856,845 (304)

SELECTIVE SEROTONIN RE-UPTAKE INHIBITORS: AN OVERVIEW

open access: yesPsychiatria Danubina, 2018
Selective serotonin re-uptake inhibitors (SSRIs) are front-line pharmacotherapies in the treatment of major depressive disorder (MDD), a disorder characterized by a persistent low mood, anhedonia and feelings of worthlessness. Since their formulation over 40 years ago, there have been several conflicting studies exploring the efficacy of these highly ...
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

An Amine-Decorated Pores Metal Organic Framework CAU-1: High and Selective CO2 Uptake

open access: yes, 2011
The amine-decorated microporous metal-organic framework CAU-1 was readily synthesized and activated using a home made efficient protocol. It exhibited a high heat of adsorption for CO2, high CO2 uptake capacity, and an impressive selectivity for CO2 over
徐芬, 司晓亮, 孙立贤
core  

Barriers and facilitators to uptake of cervical cancer screening among women accessing maternal and child health services in Kampala, Uganda [PDF]

open access: yes, 2013
Magister Public Health - MPHThe aim of the study was to explore the challenges to uptake of cervical cancer screening among women accessing maternal and child health services at Nsambya Hospital in Kampala ...
Atuhaire, Lydia
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Platform 2013 : getting evidence-based development research into use in Sub-Saharan Africa; accessible DRUSSA University research for policy-makers

open access: yes, 2013
The Development Research Uptake in Sub-Saharan Africa (DRUSSA) Programme “Platform 2013” publication provides a round-up of current evidence-based development research which can be used as a platform towards public policy influence.
Development Research Uptake in Sub-Saharan Africa (DRUSSA)
core   +1 more source

YeeD is an essential partner for YeeE-mediated thiosulfate uptake in bacteria and regulates thiosulfate ion decomposition.

open access: yesPLoS Biology
Uptake of thiosulfate ions as an inorganic sulfur source from the environment is important for bacterial sulfur assimilation. Recently, a selective thiosulfate uptake pathway involving a membrane protein YeeE (TsuA) in Escherichia coli was characterized.
Mai Ikei   +10 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Selective uptake of cholesteryl ester in plasma and liver.

open access: yes, 2013
[A] Uptake of [125I] upper panel and [3H] lower panel in plasma over 24 hrs and in tissues: liver, adrenals, testis and kidney at 24 hrs.
Yanina Langle (360584)   +6 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

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