Results 211 to 220 of about 1,856,845 (304)

COPI Coatomer Regulates Several Steps of HDL Metabolism. [PDF]

Arterioscler Thromb Vasc Biol
Panteloglou G, Zanoni P, Law CS, Woods B, Othman A, Yalcinkaya M, Norrelykke SF, Rzepiela AJ, Stoma S, Stebler M, Kerksiek A, Visentin M, Smit M, Wolters JC, Kakava S, Potapenko A, Schlumpf E, Radosavljevic S, Häusler S, Futema M, Dalila N, Tybjaerg-Hansen A, Humphries SE, Kuivenhoven JA, Sluis BV, Lütjohann D, Meier R, Robert J, Chou J, Geha RS, Shum AK, Rohrer L, von Eckardstein A.   +32 more
europepmc   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

A Novel CD147-Targeting Nanobody for Immuno-PET Imaging of Liver Cancer. [PDF]

J Nucl Med
Nambiar DM, Esparza TJ, Lee W, Chung JY, Olkowski CP, Ghaemi B, Basuli F, Shi J, Baidoo KE, Sheehan-Klenk J, Makala H, Zhang HH, Farber JM, Choyke PL, Escorcia FE, Jacobson O.   +15 more
europepmc   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Acute Ethanol Exposure Inhibits GABA Uptake in Embryonic Chicken Retina. [PDF]

Neurochem Res
Damascena ACO, Abramov AK, Pinheiro L, Dos Santos Pereira M, Trindade P, Stipursky J, De Melo Reis RA, Kubrusly RCC.   +7 more
europepmc   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Biodistribution and dosimetry of the carbon-11 labelled PARP1-selective PET radiopharmaceutical [¹¹C]AZ14193391. [PDF]

EJNMMI Res
Törnblom A, He C, Bolin M, Tzortzakakis A, Fernebro J, Li C, Fridsten S, Altena R, Axelsson R, Siikanen J, Hindorf C.   +10 more
europepmc   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source