Results 201 to 210 of about 18,127 (245)
Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat
ヘイン コー ウー, Hein Ko Oo
openalex +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Selenoprotein P receptor from rat
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1989Radioreceptor assay technology was used to show the presence in the rat of a receptor that binds selenoprotein P, a selenocysteine-containing rat plasma protein. 75Se-labeled selenoprotein P bound to testis, kidney, and liver membranes. The binding was specific in that increasing amounts of partially-fractionated rat plasma specifically displaced the ...
B, Gomez, A L, Tappel
openaire +2 more sources
Some properties of selenoprotein P
Biological Trace Element Research, 1992Selenoprotein P is a newly characterized selenoprotein. It is the first protein described to contain multiple selenocysteines. It is secreted by the liver into the plasma and turns over rapidly. Its concentration is sensitive to the selenium status of the animal. Its function is unknown.
R F, Burk, K E, Hill
openaire +2 more sources
Elevated Selenoprotein P Levels in Thalassemia Major Patients
Archives of Medical Research, 2022Previous studies have measured selenium levels and glutathione peroxidase 3 (GPX3) activity in patients with thalassemia major (TM). However, Selenoprotein P (SEPP), which is responsible for the storage and transport of selenium, has not been studied in thalassemia patients.
Gunel Talibova +3 more
openaire +2 more sources
Cellular and Molecular Life Sciences, 2000
Selenoprotein P (SeP) is an extracellular, monomeric glycoprotein containing up to 10 selenocysteine residues in the polypeptide chain. It is ubiquitously expressed in mammalian tissues, and in human plasma it accounts for at least 40% of the total selenium concentration. SeP binds to heparin and cell membranes, and is associated with endothelial cells.
openaire +2 more sources
Selenoprotein P (SeP) is an extracellular, monomeric glycoprotein containing up to 10 selenocysteine residues in the polypeptide chain. It is ubiquitously expressed in mammalian tissues, and in human plasma it accounts for at least 40% of the total selenium concentration. SeP binds to heparin and cell membranes, and is associated with endothelial cells.
openaire +2 more sources
Analysis of the Mouse Selenoprotein P Gene
Biological Chemistry, 1998In vertebrates several proteins containing a covalently bound selenocysteine residue have been identified. Among these, selenoprotein P is the most unusual one: depending on the species, 8-12 selenocysteine residues are cotranslationally integrated into the polypeptide chain. The protein was traced in rat plasma, but its role has not been worked out so
P, Steinert, D, Bächner, L, Flohé
openaire +2 more sources
Selenoprotein P and selenoprotein M block Zn2+-mediated Aβ42 aggregation and toxicity
Metallomics, 2013Aggregation and cytotoxicity of the amyloid-β (Aβ) peptide with transition metal ions in neuronal cells have been suggested to be involved in the progression of Alzheimer's disease (AD). A therapeutic strategy to combat this incurable disease is to design chemical agents to target metal-Aβ species.
Xiubo, Du +5 more
openaire +2 more sources
Rat plasma selenoprotein P properties and purification
Biochimica et Biophysica Acta (BBA) - General Subjects, 1989A selenoprotein in rat plasma, selenoprotein P, was fractionated and characterized. Plasma collected from rats 3 h post injection of 75SeO3(2-) contained one 75Se-labeled protein, selenoprotein P. Selenoprotein P was fractionated using salt precipitation, Affi-Gel Blue, and DEAE chromatography.
P A, Motchnik, A L, Tappel
openaire +2 more sources
Purification of selenoprotein P from human plasma
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1994Selenoprotein P was partially purified (> 1000-fold) from human plasma in four chromatographic steps using 75Se-labeled selenoprotein P secreted by HepG2 cells in culture as a marker. The purified preparation was injected into mice and monoclonal antibodies, which precipitated the labeled protein, were generated.
B, Akesson, T, Bellew, R F, Burk
openaire +2 more sources
Selenoprotein P: Properties, Functions, and Regulation
Archives of Biochemistry and Biophysics, 2000Selenoprotein P (SeP) is a plasma protein which contains 10 selenocysteine residues per polypeptide. It accounts for more than 50% of the selenium content in rat and human plasma but its function is still not completely understood. However, a function as an extracellular antioxidant seems most probable.
openaire +2 more sources